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Effect of voriconazole of vision of healthy volunteers
Voriconazole is a broad spectrum, triazole antifungal agent used for systemic fungal infections. It has a favourable safety profile and is available in both intravenous and oral forms. The commonest adverse drug reactions with voriconazole are changes in visual perception,...
LASEK vs. epi-LASIK for myopia: meta-analysis
Previous studies have produced inconsistent conclusions on the relative benefits between LASEK vs. Epi-LASIK. LASEK uses 20% alcohol to separate an epithelial flap from the Bowman membrane. After ablation, the epithelial flap is repositioned onto the cornea. Epi-LASIK creates the...
Beliefs and adherence to glaucoma treatment
The aim of the study was to determine adherence rates and beliefs about glaucoma and its treatment in white Americans, African Americans, white Australians and Singaporeans of Chinese descent. A cross-sectional study of 475 glaucoma patients using topical eye drops...
IR recession and prevention of lower lid retraction
The authors report the efficacy in preventing lower eyelid retraction and long-term results of a new technique of inferior rectus recession for vertical strabismus. The results for 35 patients were compared with 22 patients having conventional inferior rectus recession. Inferior...
MicroRNA mediate retinoblastoma signal transduction
MicroRNAs (miR) are small non-coding single-stranded RNA molecules, normally 22 nucleotides long. There is a large family of miR that control protein expression by binding to mRNAs, leading to their degradation. One important role of miR is in tumours where...
Cataract in patients with pseudoexfoliation syndrome
The authors present a prospective comparative study in 43 patients with (group 1) or without (group 2) pseudoexfoliation (PXF) undergoing cataract surgery. Anterior capsule samples were obtained in all patients and analysed for signs of apoptosis by using special staining...
International variations in ROP treatment
A retrospective cohort review of 48,087 premature infants weighing <1500 gm between 24 to 27 weeks gestation, from 11 high income countries in Australia, New Zealand, Canada, Finland, Israel, Japan, Spain, Sweden, Switzerland, Tuscany (Italy) and the UK . By...
Prostaglandin associated periorbitopathy
Prostaglandins are known to cause periorbital adverse effects. The aim of this retrospective case series was to compare the frequency of prostaglandin associated periorbitopathy (PAP) between bimatoprost, latanoprost and travoprost users. Five PAP findings were evaluated: upper lid ptosis, deepening...
Success rates of primary and revision transcanalicular DCR surgery
Transcanalicular laser DCR is a relatively rare procedure compared to more conventional external or endo-nasal techniques. In this article the authors examine the outcomes of revision surgery following failed transcanalicular diode laser dacryocystorhinostomy (TCDL DCR), comparing a conventional external revision...
Reduced blood flow and age-related macular degeneration
This was a prospective cross-sectional study assessing changes in blood flow velocity in patients with age-related macular degeneration (AMD) using a retinal function imager. Sixty eyes with wet AMD were compared to 53 control eyes and the average blood flow...
Liquid adhesive bandage for clear corneal cataract incisions
This paper reports a prospective randomised controlled trial of patients undergoing routine phacoemulsification with a 2.75mm clear corneal incision and followed up for 14 days postoperatively. They evaluated wound edge closure, surgically induced astigmatism and foreign body sensation after use...
