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The role of inflammation in the pathophysiology of DMO

1 February 2016 | | EYE - Vitreo-Retinal
Diabetic macular oedema (DMO) is a major cause of visual loss in diabetes, with a complex multifactorial pathogenesis. In the UK alone it is estimated that there are nearly 2.5 million diabetic patients aged over 12 years. Approximately 65,000 of...

Myasthenia gravis presenting with isolated ptosis: a poorly studied subgroup

1 February 2015 | | EYE - Vitreo-Retinal
Investigation into the cause of one isolated symptom or sign can be challenging if that particular sign may be caused by a variety of pathological processes, affecting different tissues, and presenting to different specialties. Unilateral ptosis is a case in...

Advances and developments in medical retina

1 February 2019 | | EYE - Vitreo-Retinal, EYE - General
The author provides an update on late breaking clinical trial results in neovascular age-related macular degeneration (nAMD) and presentations on diabetes management from the American Academy of Ophthalmology Retina Subspecialty Day, held during the Academy’s annual meeting in Chicago, October...

Corneal hysteresis: An emerging biomarker in the management of glaucoma

2 October 2025 | | EYE - Cornea
Corneal hysteresis (CH) is gaining recognition as a valuable parameter in the management of glaucoma. Corneal hysteresis is defined as the difference between the inward and outward pressure responses of the cornea during deformation. This measurement reflects the viscoelastic properties...

Laser corneal refractive procedures – a review

1 December 2017 | | EYE - Cataract, EYE - Refractive
Evolution of refractive surgery stays true to the quote of Theodore Roosevelt: “The more you know about the past, the better prepared you are for the future.” Refractive surgery is an evolving field, which thanks modern technologies for refining ideas...

‘The Way Forward’ champions clinicians as architects of patient-centred service redesign

1 April 2017 | | EYE - Cataract, EYE - Glaucoma, EYE - Vitreo-Retinal
The demographic time bomb poses the dilemma of how more healthcare can be delivered to the UK’s ageing population without commensurate growth in resources. The Way Forward Project provides a robust resource for clinical centres to better identify and implement...

Retinoblastoma management update (part 2): treatment, screening and surveillance, long-term follow-up and new developments

1 February 2017 | | EYE - Oncology
Retinoblastoma treatment requires significant multidisciplinary input, but early detection through raising awareness remains key to improving outcomes. In the second article of a two-part series, Manoj Parulekar discusses retinoblastoma management, screening and research. This article has been published in two...

Uveal melanoma

3 August 2023 | | EYE - Pathology, EYE - Oncology, EYE - Imaging
Uveal melanoma is the most common primary intraocular tumour. However, they are still rare, with an incidence of 2-8 per million [1]. The presence of a choroidal naevus is a risk factor for uveal melanoma [1]. Patients with choroidal lesions...

Improving eye care for children with learning difficulties: a view from SeeAbility

1 August 2019 | | EYE - General
Marek P Karas from sightloss charity SeeAbility examines why children with a learning disability do not access the eye care they need and asks how the system needs to change. Children with a learning disability are 28 times more likely...

Caring for adults with an ocular tumour

1 December 2015 | | EYE - Vitreo-Retinal
Detection If you screen for an intraocular tumour, dilate the pupil. If the patient is driving, use phenylephrine only. If the patient declines, document this in the casenotes. Don’t forget to look for sentinel vessels, which would indicate a ciliary...

Discussing treatment modalities for bilateral wet AMD

1 December 2014 | | EYE - Vitreo-Retinal
A 65-year-old lady with bilateral wet AMD and vision of 6/24 comes with an internet search about current therapies. How do you explain the various treatment modalities available? There are two NICE approved treatments for wet age-related macular degeneration (AMD)....

Don’t ignore the black lesion! It might be mucormycosis

1 June 2017 | | EYE - Cornea
Keeping mucormycosis infection in the foreground of your differential diagnosis, especially in those more vulnerable patients, will help save their lives if recognised and managed appropriately. Mucormycosis is a fulminant infection caused by the fungi of the family Mucoraceae. It...