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Analysis of risk factors for intraocular pressure rise following insertion of fluocinolone acetonide injection in uveitic patients
For this study, the authors analysed the pooled data from three phase2b / 3 multi-centre randomised controlled trials carried out over three years. Included patients had undergone at least one of the following treatments: 1) systemic therapy (corticosteroid / immunosuppressant...Shifting the paradigm of managing patients in medical retina: how real-world data can help us to improve clinical practice
The ophthalmic subspecialty of ‘medical retina’ has undergone dramatic changes in recent years. With the introduction of ranibizumab (Lucentis, Novartis), a specialty formerly dominated by laser-based therapies has been transformed to become, in large part, pharmacotherapy-based. To date, these pharmacotherapies...Eye disease patients have more opportunity than ever to take part in NHS research studies
A new report highlights how 76% of UK hospitals now offer patients the opportunity to take part in studies of eye disease to improve research and innovation. ‘Ophthalmology research in the UK’s National Health Service: the structure and performance of...
How common is empty sella in neuro-ophthalmology patients not suspected of raised intracranial pressure
The study aimed to assess how common the presence of empty / partially empty sella is amongst neuro-ophthalmology patients undergoing magnetic resonance imaging (MRI) excluding for papilledema and raised intracranial pressure (ICP). The study retrospectively reviewed case records of consecutive...
Tear film thickness after treatment with artificial tears in patients with moderate dry eye disease
In recent years artificial tear drops addressing tear film osmolarity have come onto the market. Increased tear evaporation and reduced tear volume results in tear hyperosmolarity. This triggers an inflammatory process leading to apoptosis of goblet and epithelial cells. Trehalose,...
Patients prefer vision from lasik than from smile in a contralateral-eye trial
This prospective, randomised, single surgeon, contralateral-eye clinical trial compared the results in myopic patients undergoing wavefront-guided femtosecond laser in situ keratomileusis (LASIK) in one eye and small-incision lenticule extraction (SMILE) in the fellow eye. The patient-reported outcomes with laser in...Specialist high-street eye clinics for managing patients with retinal disorders can enhance care standards
The author examines the successful introduction of community-based retinal clinic services by Manchester University NHS Foundation Trust. Dr Sajjad Mahmood, Consultant Ophthalmologist, MREH, shares experience of establishing community-based medical retina clinic services. Sight loss from age-related macular degeneration (AMD), cataract,...
Effect of intra-arterial chemotherapy drug regimens on globe salvage outcomes of retinoblastoma patients
This is a retrospective study from Shandong University, China, between May 2016 to November 2019, to compare the effect of 3-drug regimen (melphalan (MP) , topotecan (TP) and Carboplatin (CP)) of 95 patients (97 eyes) with two-drug regimen (MP and...
Meibomian gland alteration in patients with primary chronic dacryocystitis: An in vivo confocal microscopy study
Chronic dacryocystitis affects tear film functionality and can predispose to ocular surface disease, however the specific effect of chronic dacryocystitis on meibomian gland function has not been studied. This group therefore performed in vivo confocal microscopy in 28 patients’ eyes...Introducing Glaucoma Wise®: New ‘Beyond the Clinic’ Support for Glaucoma Patients Post Diagnosis
Time pressure means that clinicians have to focus on monitoring eye health and ‘fixing eyes’, limiting their ability to provide the emotional and practical support patients need. Glaucoma Wise is a free online resource that clinicians can direct their patients...Intraocular lens choice in patients who have undergone previous corneal refractive surgery
Patients who underwent vision correction in their 20s to 40s are now entering their 50s and 60s, the typical starting age for cataract development [1]. Consequently, ophthalmologists are increasingly encountering patients whose corneal profiles have been surgically altered, requiring advanced...
