You searched for "gene therapy"
Ocular adnexal mantle cell lymphoma
In this study the authors compare primary ocular adnexal (OA) mantle cell lymphoma (MCL) with initially systemic MCL occurring over a 30-year period. MCL is a rare form of lymphoma accounting for 5-11% of OA lymphomas and therefore knowledge of...
Yolk sac tumours of the orbit and sinonasal tract
This paper outlines two case reports of patients with yolk sac tumours (YSTs) and carries out a review of the literature on this rare malignancy. YSTs are a type of germ cell tumour and primarily occur in the gonads. Ten...
Visual outcomes and predictors in optic pathway glioma
This is a retrospective study of 60 paediatric optic pathway glioma (OPG) patients (NF1 or sporadic) presenting to Great Ormond Street between 2003-2017. Median follow-up was 82 months. Analysis was divided into best and worst eye vision representing level quality...
Using bupivacaine to the medical rectus in addition to lateral rectus recession for convergence insufficiency type intermittent exotropia
This is a retrospective study of 60 paediatric optic pathway glioma (OPG) patients (NF1 or sporadic) presenting to Great Ormond Street between 2003-2017. Median follow-up was 82 months. Analysis was divided into best and worst eye vision representing level quality...
Intra-arterial carboplatin therapy not associated with hearing loss
The aim of this study was to determine if administration of intra-arterial carboplatin (IAC) affected the hearing of children being treated for retinoblastoma. This was a prospective study in which 22 of 40 consented children completed therapy. Hearing was tested...
Atopic keratoconjunctivitis (AKC) and ocular surface squamous neoplasia (OSSN)
The authors present two cases of invasive OSSN in patients with severe AKC. Case 1 was a 73-year-old male with severe AKC and atopic eczema who developed a suspicious papillary-like limbal lesion in the left eye. He had an excisional...An anterior segment lump: a diagnostic and treatment challenge
Case presentation A 50-year-old female presented to eye casualty with a lump on the left medial lower eyelid with associated redness and occasional bleeding. The lump was present for a few months with recent enlargement (Figure 1). Her past medical...
Stereotactic radiotherapy for polypoidal choroidal vasculopathy
Polypoidal choroidal vasculopathy (PCV) is a variant of neovascular AMD. It is a disease of choroidal vasculature characterised by abnormal branching vascular network with aneurysmal dilatations (polyps). Features of PCV include pigment epithelial detachments (PED), subretinal fluid (SRF) accumulation and...Leadership skills training through the COECSA-RCOphth LINK
The Lead Forward project was an initiative of the VISION 2020 LINKS Programme, funded by the Department for International Development (DFID) via the Tropical Health Education Trust (THET). It aimed to improve the quality of medical leadership within VISION 2020...
Orbital Schwannomas
This is a large case series of orbital Schwannomas managed at a single centre over a 26-year period. Twenty Schwannomas are reported, all but one of which was managed surgically. The tumours were all benign, had an insidious onset and...
Visual outcomes, visual fields and optical coherence tomography in paediatric craniopharyngioma
This study reviews the visual outcomes of ten patients under the age of 18 years with craniopharyngioma. The paper also reviews the correlation between visual field (VF) testing and optical coherence tomography (OCT) examination and evaluates the role of OCT...
