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Ocular surface special: Ocular manifestations of Stevens-Johnson syndrome

Stevens–Johnson syndrome (SJS) is an uncommon dermatological emergency on the same clinical spectrum as toxic epidermal necrolysis (TEN). SJS is characterised by an acute, immune-mediated attack on the skin and mucous membranes, producing a rapidly progressive erythematous eruption with blistering...

Ciclosporin and dry eye

Dry eye has an estimated prevalence of between 5 and 50% worldwide and has physical, psychological and socioeconomic consequences for the human population [1]. Loss of tear film homeostasis with associated ocular surface inflammation causes symptoms ranging from ‘tired’ eyes...

Building data infrastructure for eye research in the NHS: Real-world lessons from the Liverpool Eye Data Platform

The Liverpool Eye Data Platform demonstrates how governance-compliant infrastructure can bring together routinely-collected, siloed NHS eye data. Routine care delivered across the NHS generates vast amounts of clinical data within a healthcare system that is uniquely characterised by comprehensive population...

The extended role of the specialist ophthalmic photographer

The prevalence of certain retinal conditions such as diabetic retinopathy and age-related macular degeneration (ARMD) is projected to grow substantially over the next decades. Estimates for the projected growth in burden on eye services for diabetic retinopathy and neovascular ARMD...

NHS England national ophthalmic diagnostics and imaging data collection analysis

The National Physiological Science Data Collections are part of NHS England’s Diagnostic Transformation programme which was established following Professor Mike Richards review of Diagnostic services. A key recommendation was to establish data collections to make up for the lack of...

The clues of the eye – what is medical ophthalmology?

The author looks at the increasingly significant role of medical ophthalmologists and the importance of integrative healthcare. The eye is a remarkable organ, and for decades we have been discovering intimations of pathology existing elsewhere in the body [1] simply...

175 years of Ernst Fuchs: The man behind the eponyms

14 June 2026 marked 175 years since the birth of Professor Ernst Fuchs: a teacher, writer, pathologist and one of the great founders of modern ophthalmology, whose name echoes through clinics, exams and theatres worldwide to this day. Most doctors...

Large language models in ophthalmology

Traditional artificial intelligence (AI) models typically require large amounts of labelled data for training. For example, to develop a model capable of detecting macular pathologies on optical coherence tomography scans, thousands of scans would need to be manually labelled by...

Regulatory approval for the use of AI as a medical device

A study led by researchers at Moorfields Eye Hospital and UCL Institute of Ophthalmology examined 36 ‘artificial intelligence as a medical device’ tools approved by regulators in Australia, Europe and the US, identifying that 19% had no published peer-reviewed data...

Artificial intelligence co-creation for educational learning tools and targeted simulators

Artificial intelligence (AI)-powered tools are becoming increasingly common within clinical practice and medical education, and using AI in simulation as a pure learning tool and for assessment has been widely discussed. Targeted, efficient use of such tools has been shown...

When the chatbot gets it wrong: Navigating AI-generated health misinformation in ophthalmology

Patients are beginning to turn to large language model chatbots for healthcare information. As clinicians, we are not only required to know when they are wrong, but why they are wrong – and what we can do about it. Recently,...