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Two-year GATHER2 data: anatomical gains, functional questions for avacincaptad pegol in geographic atrophy

Geographic atrophy (GA) secondary to age-related macular degeneration (AMD) remains a leading cause of irreversible central vision loss, and complement dysregulation has long been implicated in its pathogenesis. In 2023, the US FDA approved the first two GA therapies, both...

A paediatric case of central retinal artery occlusion following antibiotics and decompression surgery for orbital cellulitis

Orbital cellulitis is an ophthalmic emergency that warrants urgent management in the hospital setting [1]. This occurs more frequently in the paediatric population where it is often secondary to sinus infections. Delay in treatment could result in severe complications including...

In conversation with Captain Gary Dyson

Captain Gary Dyson, Chief Pilot of the Orbis Flying Eye Hospital, spoke to Chris Henson about his 22-year stint flying the plane, its role at the cutting edge of aviation and medical technology, and how Orbis plan to continue to...

My ophthalmology elective: East to West

I was fortunate to be able to complete my elective in three different parts of the world: the UK, Vietnam and Pakistan. I spent three weeks at Bristol Eye Hospital (BEH), two weeks at Cho Ray Hospital in Ho Chi...

Ophthalmology specialty training applications: a costly affair?

Ophthalmology is one of the most competitive specialties to pursue training in worldwide. In the United Kingdom, the ST1 entry national selection competition ratio for the past few years has ranged between four to five applicants per post [1]. The...

Getting one’s eye in

Lisette Bijma, Sister in the Eye Emergency Department at John Radcliffe Hospital, explains how COVID-19 provided a ‘baptism by fire’ and enabled fundamental and positive changes to the running of the department. Five years ago, I arrived in the UK,...

The symbolism of eyes in Halloween traditions and popular culture

Halloween is a festival steeped in symbolism. Pumpkins, skeletons, ghosts and witches dominate the seasonal iconography, each representing broader cultural anxieties about death, darkness and the supernatural. Among these motifs, the eye, often depicted as glowing, disembodied or grotesquely exaggerated,...

Specialist high-street eye clinics for managing patients with retinal disorders can enhance care standards

The author examines the successful introduction of community-based retinal clinic services by Manchester University NHS Foundation Trust. Dr Sajjad Mahmood, Consultant Ophthalmologist, MREH, shares experience of establishing community-based medical retina clinic services. Sight loss from age-related macular degeneration (AMD), cataract,...

Real world data of post-IVT endophthalmitis, from a nurse-delivered intravitreal injection service

Introduction Intravitreal injection of neutralising anti-vascular endothelial growth factor (VEGF) antibody was licenced more than a decade ago, and over the years there has been proportionate increase in the number of intravitreal injections [1]. Injection of a therapeutic agent through...

Genetic therapy gives infants life-changing improvements in sight

Four young children have gained life-changing improvements in sight following treatment with a pioneering new genetic medicine through Moorfields Eye Hospital and UCL Institute of Ophthalmology, with the support of MeiraGTx. The children were born with a severe impairment to...

Iris-claw IOL implantation: Indications, outcomes and complications

This article has been verified for CPD. Click the button below to answer a few short questions and download a form to be included in your CPD folder. A comprehensive study evaluating the clinical indications, visual outcomes and complication rates...

The challenge of chorioretinal folds in virtual eye clinics

Chorioretinal or choroidal folds are parallel striations involving the retina, retinal pigment epithelium (RPE), Bruch’s membrane, and inner choroid [1]. They can arise from compressive stress on these layers, and their presence often serves as a diagnostic marker for underlying...