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New speaker for the SEE Summit
The Association of British Dispensing Opticians (ABDO) has announced another speaker for the SEE Summit. Former GP Dr Matt Sawyer runs an environmental sustainability consultancy, SEE Sustainability, working to improve human and planetary health.
Ophthalmology for Medical Students DVD
Medical students spend far too little time in clinical ophthalmology, barely a week in a whole five year course. A week usually taken up by learning very basic facts about the eye and about the specialty, which means that any...
Stromal cell alignment in damaged cornea
Stromal keratocytes are responsible for wound healing in the cornea following damage. Keratocytes at the site of injury become activated and differentiate to myofibroblasts which secrete extracellular matrix (ECM) to close the wound, a response mediated by transforming growth factor...
Mast cells in Graves’ ophthalmopathy
Graves’ ophthalmopathy (GO) is a potentially sight-threatening ocular disease, occurring in patients with hyperthyroidism due to Graves’ disease. Also known as thyroid-associated ophthalmopathy, GO is characterised by orbital infiltration by immune cells including macrophages, T cells and plasma cells, which...
Bleb-related changes in upper lid position
This is a review of five patients with upper lid ptosis or lid retraction secondary to large filtering blebs post-trabeculectomy. The authors review each case and apply a model to analyse the separate forces acting on the upper lid to...
Bioengineered human tissue
This is a literature review of the current status of tissue engineering related to ocular and oculoplastic reconstructive surgery. The authors describe the process of bioengineering for tissue reconstruction. The aim is to reproduce functional tissue by the use of...
Association between serum 25-hydroxyvitamin D levels and age-related cataracts
Cataractogenesis occurs as a result of ageing, smoking, exposure to UV radiation and genetic predisposition. Antioxidants can reduce the cataract risk as found in animal models and humans and vitamin D is one of them. This epidemiological study based in...
SLT vs. topical treatment with prostaglandin analogues in the management of PACG
Selective laser trabeculoplasty (SLT) has been shown to be useful in the management of primary open angle glaucoma (POAG), but its use in primary angle closure (PAC) / primary angle closure glaucoma (PACG) has yet to be validated. Narayanaswamy et...
Is virtual reality perimetry as reliable as static perimetry in detecting neurological visual field loss?
This study compares agreement between virtual reality perimetry (VRP) and static automated perimetry (SAP) in a variety of neuro-ophthalmological conditions. For this work the Order of Magnitude (OM) VR-based visual field assessment system was used which has been developed by...
Choroideremia in women
The authors report a questionnaire-based study of female carriers of choroideremia, an X-linked inherited chorioretinal dystrophy. As an X-linked condition the full clinical features are predominantly seen in men but a proportion of women suffer some morbidity, likely due to...
Transcriptomic and regulatory gene associations in open angle glaucoma
The authors report a study utilising a publicly available whole exome sequencing dataset of 28 patients with primary open angle glaucoma (POAG) and seven healthy control patients, and a transcriptomic dataset from the trabecular meshwork of four POAG patients and...
