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Real-world experience of using ciclosporin-A 0.1% in the management of ocular surface inflammatory diseases

This is a retrospective study of patients with ocular surface inflammatory diseases (OSIDs) treated with IKERVIS in a single centre between 2016 to 2019 with at least six months follow-up. Clinical outcome was defined as successful (resolved or stable disease),...

Aquaporin-4 antibody testing in isolate optic neuritis

The authors present a retrospective case review of first presentation isolated cases of optic neuritis tested for aquaporin-4 antibody across two centres over a nine-year period. Exclusion criteria included known diagnosis or other manifestations of neuromyelitis optica spectrum disorder. Two...

Tocilizumab in Graves’ orbitopathy

This prospective European study looks at the response to tocilizumab in corticosteroid-resistant disease. Tocilizumab (TCZ) is a monoclonal antibody that competitively inhibits IL-6 binding to its receptor. Unlike teprotumumab, the advantage of TCZ is that it is already used within...

Comparison of bupivacaine injection vs. mini-tenotomy for small angle deviations

Bupivacaine hydrochloride is an aminoacyltype local anaesthetic. Injection into extraocular muscles elicits a myotoxic response destroying striated muscle fibres but sparing satellite cells, nerves and vessels. Preserved satellite cells proliferate to form new muscle fibres, causing muscle hypertrophy and greater...

Tocilizumab effectiveness in paediatric non-infectious uveitis: data from the International AIDA Network Registries on ocular inflammatory disorders

Medical records of 15 paediatric patients (onset before age of 16) affected by refractory non-infectious uveitis (NIU) and treated by tocilizumab (TCZ) were reviewed. Data were extracted from the international AIDA Network for uveitis registry and Behcet’s disease registries. They...

Manchester Royal Eye Hospital first in UK to use ultra-wide field OCT angiography machine in patient facing setting

Manchester Royal Eye Hospital announces it is the first in the UK to utilise the ultra-wide field OCT angiography machine, the Xephilio OCT-S1 from Canon, in a patient facing setting.

The role of injection assistant devices in establishing a nurse-led AMD service

The author shares his experience of setting up a nurse-led service to deliver anti-VEGF intravitreal injections and how injection assistant devices supported training. Age-related macular degeneration (AMD) has become a leading cause of irreversible blindness [1]. It is estimated that...

ChatGPT cannot pass FRCOphth examinations: implications for ophthalmology and large language model artificial intelligence

Large language models are generating a lot of hype for artificial intelligence, but can they assist patients and practitioners in ophthalmology? Introduction Deep learning (DL) has emerged in ophthalmology as an exciting form of artificial intelligence (AI) most commonly applied...

What's trending Jun/Jul 2025

A round-up of the eye-related hot topics that have been trending on social media over the last few weeks. #Inspiration #FlyingEyeHospital It was with great sadness that I read about the passing of Dr David Paton at the age of...

App and web service recommendations

This article offers some app and web service suggestions. A few are new and others well established, but all offer useful features. Messaging for teams Many businesses provide their employees with instant messaging services to allow calling, messaging and collaboration....

Orbis celebrates International Day of Friendship

International eyecare charity Orbis recognises the importance of strong bonds on International Day of Friendship 2023.

The science of glaucoma management: highlights of the 2020 Moorfields International Glaucoma Symposium

Held earlier this year, the 12th annual Moorfields International Glaucoma Symposium provided a forum for advanced clinical and scientific exchange in glaucoma management. The authors describe the key presentation themes and debates, highlighting specific topics of interest to glaucoma specialists....