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A prospective trial of adjuvant therapy for high-risk melanoma
Patients diagnosed with iris, ciliary body or choroidal melanoma of high-risk tumour cytogenetics (monosomy 3>/= 20% of cells), were treated with adjuvant low-dose dacarbacine (DTIC) and interferon –alpha-2b (IFNA-2b), following primary treatment (enucleation, brachytherapy or resection). DTIC was given intravenously...
Superior oblique tuck procedure
A retrospective study was conducted of superior oblique (SO) tuck as a primary and secondary surgery over a 25-year period involved 162 eyes of 162 patients. Two thirds were male. Mean age at surgery was 45.94 years. The left eye...
Graded Andersons procedure for nystagmus
The authors performed a recession of yoked muscles in patients with idiopathic infantile nystagmus (IIN) in a graded manner based on the amount of head turn. This was a retrospective case series of 37 patients; 26 males, 11 females aged...
Visual outcome and surgical results in children with Marfan Syndrome
Eighty-two eyes of 41 patients with a genetically proven diagnosis of Marfan syndrome were retrospectively analysed. Twenty-seven had bilateral subluxation and 14 received lensectomy. Follow-up was three years. Mean visual acuity (VA) was 0.1 ±0.7 logMAR in patients with normal...
Accuracy of intraocular lens power calculations in paediatric eyes
A study comparing the accuracy of the SRK II, SRK/T, Hoffer Q, Holladay 1, T2 and Super formula in predictive refractive outcomes in children undergoing primary IOL insertion into the capsular bag following cataract surgery. A total of 377 eyes...
Examination of optic disc drusen using computer-based fundus analysis
This case-control study analysed the optic disc angioarchitecture in optic disc drusen (ODD) using computer-based fundus examination. A group of ODD patients were compared to a group of healthy controls with normal optic discs. The cohort included 30 healthy volunteers...
Ocular adnexal marginal zone b-cell lymphoma
This is a multicentre retrospective study of seven eye centres of 689 patients with ocular adnexal extranodal marginal zone b-cell lymphoma (OA-EMZL). The median follow-up time was 42 months and the median age was 62 years. Fifty-five percent were women;...
Duane’s retraction syndrome (DRS)
The authors aimed to review all cases of DRS presenting to a tertiary paediatric eye clinic in South Africa during a 20-year period. This was a retrospective study in Cape Town involving 120 patents (80 mixed race, 24 black and...
Surgical results in spinocerebellar ataxia (SCA)
Patients with SCA frequently develop ocular motility abnormalities including nystagmus, abnormal smooth pursuits, dysmetric saccades, divergence paresis and ophthalmoplegia. Incidence of diplopia is higher in SCA type 3. The purpose of this study was to evaluate surgical responses and outcomes...
Outcome of nasolacrimal probing in older children
The authors aimed to determine the success of nasolacrimal duct obstruction (NLD) probing in a cohort of patients older than four years with simple membranous obstruction. Eighteen patients were included in this retrospective study aged 5.6 years on average (4.1-10.6)....
Effect of blue-light filtering intraocular lenses on age-related macular degeneration
This is a retrospective cohort study evaluating whether blue-light filtering (BLF) intraocular lenses (IOL) offer prophylaxis for neovascular age-related macular degeneration (nAMD). The study included 11,397 eyes of 11,397 patients with a mean age of 75.4 ±8.3 years that underwent...
