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OCT Angiography in Retinal and Macular Diseases

OCT angiography (OCT-A) is based on the concept that in a static eye, the only moving structure in the fundus of the eye is blood flowing through the vessels. This book explains how the technique allows a depth-resolved analysis and...

Ocular complications in retinal vasculitis

In this retrospective study the authors aimed to characterise the incidence rates of visual loss and ocular complications associated with retinal vasculitis (RV – annual incidence of 1-2/ 100000/ per annum). A secondary objective was to compare the visual outcomes...

High dose (2.5mg) bevacizumab for postradiation cystoid macular oedema

The authors present a retrospective, interventional case series investigating the efficacy of high dose (2.5mg/0.1ml) intravitreal bevacizumab in the treatment of persistent postradiation (Iodine-125 plaque brachytherapy for uveal melanoma) cystoid macular oedema (CME). Persistent CME was defined as increased or...

Predicting causes and prognosis in cases of optic disc swelling

The authors reviewed 93 consecutive cases with optic disc swelling (ODS) with the purpose of comparing the clinical manifestations and prognosis between cases. The aim was to understand the differences in frequency and clinical features of ODS, relating these to...

Comparison of central laminar thickness in optic neuropathy and normal eyes

The study compares central laminar thickness (LT) among patients with glaucomatous optic neuropathy (GON), patients with non-GON and normal subjects. The non-GON group comprised eyes with demyelinating optic neuropathy (ON), anterior ischaemic ON, compressive ON, Leber hereditary ON and traumatic...

Functional visual field loss using automated static perimetry

Functional visual field loss is traditionally assessed by kinetic perimetry, typically producing spiralling isopters. This study looked at the spatial distributions of functional field deficits using automated static perimetry. A retrospective review of automated perimetry records was conducted using a...

Diagnosis of amiodarone-associated optic neuropathy

Amiodarone is a widely used anti-arrhythmic drug. Several case reports describe optic neuropathy which has been linked to its use. This case series discusses the diagnosis of amiodarone-associated optic neuropathy (AAON) and its potential impact on cardiac therapy. The authors...

Association between neuro-ophthalmology signs and chronic ataxia in children

Neuro-ophthalmological signs (N-OS) occur commonly in children with chronic ataxia. This study describes the N-OS and their frequencies, in general and by specific disease aetiology in paediatric patients with chronic ataxia. In total, 184 patients under the age of 17...

A novel way to diagnose optic neuropathies using Bruch’s membrane opening

Differential diagnosis of optic neuropathies can be challenging but is crucial for the correct management of the underlying disease and prevention of further damage. Bruch’s membrane opening (BMO) was recently discovered as the anatomical border of the optic disc. BMO...

Validity of coding in neuro-ophthalmology within large administrative datasets

A systematic review of validation studies of the International Classification of Disease (ICD) coding system, ICD-9 and ICD-10 is presented by the authors. Three searches were conducted based on three concepts, firstly health administration claims and ICD codes, secondly diagnostic...