You searched for "gene therapy"
Choosing a subspecialty
It is quite worrying how many registrars reach the final years of training without choosing a subspecialty. Sometimes this is because they love everything and cannot countenance giving any of it up, but more commonly this is due to various...
Effect of intra-arterial chemotherapy drug regimens on globe salvage outcomes of retinoblastoma patients
This is a retrospective study from Shandong University, China, between May 2016 to November 2019, to compare the effect of 3-drug regimen (melphalan (MP) , topotecan (TP) and Carboplatin (CP)) of 95 patients (97 eyes) with two-drug regimen (MP and...
Undetected retinoblastoma management following vitrectomy
This retrospective study from a single-centre referral university hospital in Germany analysed data collected between 1991-2019 to comment on management and complications of undetected retinoblastoma eyes following vitrectomy. The 10 patients included had a mean age of 36.1 months (range...Neurofibromatosis with multiple bilateral choroidal nevi and literature review
The aim is to present a case of neurofibromatosis type-1 (NF-1), also known as von Recklinghausen disease, who presented with bilateral multiple choroidal nodular nevi following chemotherapy and mastectomy for breast cancer. Neurofibromatosis type-1 presents as a wide range of...The role of virtual Rb-NET Multidisciplinary Team meetings in the management of children with retinoblastoma in low- and middle-income countries
A selection of participants in an MDT meeting with Uganda. In 2017 the LINKS Programme developed a new network of LINKS to support and coordinate action against retinoblastoma (Rb) in response to requests from low- and middle-income countries (LMICs), called...Quiz Oct/Nov 2024
History An 83-year-old female was previously treated by surgical excision and plaque brachytherapy for her left conjunctival lesion. She presented to her ophthalmologist with a recurrence some years later and underwent a lid sparing orbital exenteration, which was sent to...
Quality of life concerns after uveal melanoma diagnosis
The authors sought to investigate factors associated with Quality Of Life (QOL) after initial diagnosis of uveal melanoma (UM) using prospectively collected data between September 2011-May 2016. They included 201 participants referred for radiotherapy after UM diagnosis by an ophthalmic...Establishing an intra-arterial chemotherapy service for children with retinoblastoma in Nigeria for the first time
This is the first in a series of three articles (see Part 2 here) about strengthening eye health services in Nigeria through collaboration with the LINKS and Networks run at the International Centre for Eye Health, London School of Hygiene...My top five: Emerging alternatives to manage and treat nAMD
Wet (exudative or neovascular) age-related macular degeneration (AMD) is characterised by choroidal neovascularisation, in which new blood vessels from the choroid invade through Bruch’s membrane. These blood vessels proliferate beneath or through the retinal pigment epithelium (RPE), causing patients to...My Top Five: Emerging alternatives to manage and treat nAMD
Wet (exudative or neovascular) age-related macular degeneration (AMD) is characterised by choroidal neovascularisation, in which new blood vessels from the choroid invade through Bruch’s membrane. These blood vessels proliferate beneath or through the retinal pigment epithelium (RPE), causing patients to...
