Saccades and contrast sensitivity in retinoblastoma survivors
Reviewed by Lauren Hepworth

The authors report a cross-sectional study, which recruited children aged 5 to 18 years old who completed treatment completion for retinoblastoma more than six months ago. Exclusion criteria included bilateral enucleation and pre-existing conditions associated with cognitive impairment. A total of 11 individuals were recruited from a pool of 13. Demographics, ocular data, disease course, treatment modalities and outcomes were collected. Participants received an ophthalmic assessment including uniocular visual acuity, saccades using eye tracking and uniocular contrast sensitivity. Six participants were female and the mean age was 11 years old. Treatment modalities included uniocular enucleation in 73% and chemotherapy in 91% of cases. Median binocular visual acuity best corrected was 0.0logMAR (6/6 Snellens equivalent). All participant had decreased contrast sensitivity based on the cut off for Cardiff contract sensitivity. All participants able to complete saccadic assessment (n=10) were decreased in one or more saccadic parameters; accuracy, latency and / or velocity. This study has reported on the wider elements of visual function in addition to visual acuity. The authors hypothesise whether reduced contrast sensitivity and impaired saccades may occur as a result of related ocular comorbidities and / or chemotherapy treatment. Further longitudinal research is required to assess these wider elements of vision to identify risk factors and rehabilitation / support options.

Characterization of vision in pediatric retinoblastoma survivors beyond visual acuity.
Raynolds M, Wise J, Wu T, et al.
JOURNAL OF THE AMERICAN ASSOCIATION FOR PEDIATRIC OPHTHALMOLOGY AND STRABISMUS
2023;27:188.