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Moorfields Eye Hospital, UCL Institute of Ophthalmology and Topcon Healthcare, Inc. launch Cascader Limited to advance AI-driven eyecare and Oculomics

Moorfields Eye Hospital NHS Foundation Trust, the UCL Institute of Ophthalmology (IoO), and Topcon Healthcare today announced the launch of Cascader Limited, a new medical technology company that aims to transform the detection and management of eye disease through artificial...

Ophthalmology survey results June/July 2019

Firstly may I thank all of you who took the time to answer the survey. I hope you will agree that the findings are very interesting. From a medicolegal perspective we always consider the Bolam test which can be summarised...

Traumatic ‘toy’ gun injury leading to permanent vision loss

Pseudoxanthoma elasticum (PXE) is a progressive, inherited disorder of connective tissue that affects the skin, cardiovascular system and retina. Ocular manifestations of the disease are related to Bruch’s membrane, a thin elastic tissue layer located between the retinal pigment epithelium...

Innovations in posterior uveitis: In conversation with Dr Colin Chu

A research team has been awarded significant funding by the National Institute for Health and Care Research (NIHR) to develop an innovative drug-device combination that aims to revolutionise how individual immune cells are monitored and treated in patients at Moorfields...

Perioperative nursing considerations for ocular patients on GLP-1 and SGLT2 inhibitor medications

New antihyperglycaemic drugs are now increasingly used to treat individuals with and without diabetes mellitus to reduce their cardiovascular and renal morbidity and mortality [1]. These include glucagon-like peptide-1 receptor agonists (GLP-1 RAs) and sodium-glucosecotransporter-2 (SGLT2) inhibitors. Glucagon-like peptide-1 receptor...

Retina Subspecialty Day highlights from the RCOphth 2026 Annual Congress

Implementation of biosimilars in NHS retinal services A NHS England (NHSE) perspective Luke Nicholson (Moorfields Eye Hospital) explained that the NHSE perspective overall is structured on best value medicine for the patient and system, accounting for a finite budget and...

Treatment of diabetic macular oedema

Diabetic macular oedema (DMO) is a common complication associated with diabetic retinopathy, and the most common cause of visual impairment in diabetes [1]. With predicted rising levels of diabetes (in England by 2025 the estimated population with diabetes will be...

Genetic profiling for personalised healthcare solutions in AMD – an update

Age-related macular degeneration (AMD) is a multifactorial condition influenced by genetics and lifestyle factors (Table 1). This article outlines several recent advances in AMD genetics, as well as evolving therapeutic concepts and established practical measures for the treatment and /...

The clues of the eye – what is medical ophthalmology?

The author looks at the increasingly significant role of medical ophthalmologists and the importance of integrative healthcare. The eye is a remarkable organ, and for decades we have been discovering intimations of pathology existing elsewhere in the body [1] simply...

Outcomes of adult new-onset strabismus presenting acutely

This study evaluated causes, neuroimaging rates and results, and clinical courses of adults presenting to an ophthalmology emergency department with diagnosis of new-onset strabismus. This was a retrospective study of 557 adults (54.8% male) with mean age of 57.3 ±16.7...

The fragile p-value

Abdus Samad Ansari explores the limitation of the p-value and the application of the fragility index in clinical trials. Clinical trials and tribulations? The restoration of vision or more purely the gift of sight is an aspect of care that...

Paediatric choroidal neovascular membrane secondary to optic disc drusen

Choroidal neovascular membrane (CNVM) is a rare cause of visual impairment in paediatric populations and predominantly affects individuals aged over 50. CNVM is defined as the pathologic growth of new abnormal blood vessels which extend from the choroid and break...