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Ovarian hormones drive onset of Sjogren’s disease in mice
Sjogren’s syndrome (SS) is a debilitating, sight-threatening, systemic autoimmune disease with no effective treatment available. SS is characterised by lacrimal gland lymphocytic infiltration and epithelial cell death, as well as by the presence of serum autoantibodies. Patients have severe dry...
Correlation between peak intraocular pressure following water drinking test and pulsed methylprednisolone therapy
Steroids have long been known to cause increased intraocular pressures (IOP) in susceptible patients. Intravenous methylprednisolone is used to treat many rheumatological conditions and one of the risks is raised intraocular pressure. It would be useful to find patients at...
Amblyopia risk factors with nasolacrimal duct obstruction in newborns
This study compares amblyopia risk factors in 1) newborns with congenital nasolacrimal duct obstruction (CNLDO) and age-matched healthy controls, 2) newborns with unilateral and bilateral CNLDO and 3) affected eye and fellow eye of newborns with unilateral CNLDO. The authors...
Unusual case presentation of arteritic anterior ischaemic optic neuropathy
The authors present a single case of an 84-year-old man with arteritic anterior ischaemic optic neuropathy, but with unusual features on temporal artery biopsy. He presented with a three-day history of sudden onset of loss of vision in his right...
Presentation features of ocular neuromyotonia in children
The authors report five cases of ocular neuromyotonia (ON) in children following radiation treatment for brain tumours. Children were aged four, nine, twelve, five and nine years. Three had craniopharyngioma, one had fourth ventricle ependymoma and one had posterior fossa...
Acute comitant esotropia as the presenting sign of diffuse intrinsic pontine glioma
The authors present four children with acute comitant esotropia (AACE) associated with diffuse intrinsic pontine glioma. All were treated with radiation therapy and all subsequently died due to the tumour. Children were aged 5, 5, 4.5 and 11 years. General...Should points for simulated surgery be removed from the ophthalmology ST1 evidence folder?
The benefits of the Eyesi surgical simulator by Haag-Streit UK for early career ophthalmology speciality trainees are well-established, allowing for the practice of cataract and vitreoretinal surgery in a controlled, risk-free environment. Whilst the Eyesi is an invaluable resource for...
Optical Coherence Tomography: A Clinical and Technical Update
This book is a comprehensive review of the clinical and scientific aspects of optical coherence tomography (OCT). The 255 pages are divided into 11 chapters, each written by a different group of authors. Part I provides viewpoints on the clinical...The results of the last survey Aug24
In the first case we were faced with a 55-year-old patient with narrow, potentially occludable drainage angles, no significant cataract, and persistently raised intraocular pressures (IOPs) of 28mmHg with early disc compromise, and normal vision in each eye. It is...
Can diuretics increase the risk of acute angle closure glaucoma?
Diuretics, used widely in the treatment of hypertension, oedema, heart failure and liver failure, have been implicated in case reports in scientific literature to be linked to bilateral acute angle closure glaucoma (AACG). The aim of this study was to...
Evaluation of a service providing sight impairment registration for stroke survivors
This service evaluation study of a hospital single centre stroke service was undertaken to determine reasons for declining sight registration, whether patients feel supported without registration and determine changes needed to improve registration processes. A review of existent data was...
