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New developments

To reflect the fact that this column consists of not just web links, but also mobile and general technology content we have changed the name from Internet to ‘Tech Review’. In keeping with the title, this issue includes a mixture...

Lines, dots, spots and rings in ophthalmology: understanding eponyms

Eponymous names are familiar to all who have undergone undergraduate and postgraduate training in medicine. The ability to name a few allows one to stand out among your peers and rare, or not so rare, eponymous syndromes are a favourite...

Conference Preview: UKISCRS, UKISOP and YOP 2025

London’s calling, and we will be rejoining the United Kingdom & Ireland Society of Cataract & Refractive Surgeons (UKISCRS), the Young Ophthalmologists Programme (YOP), and United Kingdom & Ireland Society of Ophthalmic Practitioners (UKISOP) between 12–14 November. The former will...

My top five eye-related webinars during lockdown

1. Alcon Experience Academy The Alcon Experience Academy ran a non-promotional educational series from 12 May to 23 June 2020. Being mildly biased as a junior trainee, this has to be rated by far the best series due to its...

My Top Five: Eye-related webinars during lockdown

1. Alcon Experience Academy The Alcon Experience Academy ran a non-promotional educational series from 12 May to 23 June 2020. Being mildly biased as a junior trainee, this has to be rated by far the best series due to its...

Exploiting nature’s randomised trials of eye disease

Confounding and reverse causation in observational ophthalmic epidemiology Traditional observational studies are inherently limited in establishing a causal effect of an exposure on an outcome of interest. One fundamental limitation is confounding, whereby causation is incorrectly attributed to a third...

RTP801 as a neuroprotective and axon regenerative treatment

This paper describes the neuroprotective and axon regenerative effects of siRTP801, which is a translatable small-interfering RNA (siRNA) targeting mTOR negative regulator; RTP801, through in-vivo and in-vitro models. In-vivo studies involved an optic nerve crush rat model with intravitreal injections...

Outcomes of cataract surgery in patients with uveitis

This is a systematic, evidence-based literature review and meta-analysis, looking at the visual outcomes (vision 20/40 or better) of cataract surgery in uveitic eyes. The authors searched MEDLINE, EMBASE, CINHAL and CENTRAL, including English language and human studies only. They...

Customised orbital implants

This is a literature review of the outcomes of orbital fracture repairs using custom-made orbital implants. Customised implants were manufactured in one of three ways, all using a 3D printer; manual moulding of an implant based on a 3D-printed model...

Submacular haemorrhage associated with nAMD: A meta-analysis and meta-regression on use of tPA and anti-VEGFs

The aim of this study was to evaluate the efficacy of a combination of tPA and anti-VEGF in the treatment of submacular haemorrhage (SMH) associated with neovascular age-related macular degeneration (nAMD). A systematic review meta-analysis following PRISMA guidelines, focusing on...

Efficacy of BT as a treatment for cranial nerve palsy in acute and chronic cases

The authors performed a meta-analysis of all patients’ treatment with botulinum toxin (BT) for cranial nerve palsy (CNP) to determine the efficacy of BT in the treatment of CNP due to a variety of causes. The search identified 1129 articles...

Junior doctors in emergency departments lack confidence when managing ophthalmic emergencies

This systematic review assessed the confidence of doctors in the UK working in emergency departments (EDs) to manage ophthalmic emergencies, with secondary outcomes looking at doctor’s confidence in performing fundoscopy and using the slit-lamp, and training received in the ED....