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Who will benefit from cataract surgery?

The need for cataract surgery is expected to rise dramatically in the future due to the increasing proportion of elderly citizens and increasing demands for optimum visual function. The aim of this study was to provide an evidence-based recommendation for...

Trends in Opthalmology hosts Grand Ball in honour of Sir Harold Ridley 70th anniversary

Sir Harold Ridley spent his working career at St Thomas' and Moorfields Hospital specialising in ophthalmology. During World War II, Ridley saw Royal Air Force casualties with eye injuries and observed that when splinters of acrylic plastic from aircraft cockpit...

COVID-19 elective oculoplastic consent proforma

The advent of COVID-19 will continue to impose major adaptations in how we as surgeons practise and offer elective surgery going forward. In addition to how we try to adapt to make our practice as safe for the patient and our teams as...

The Retinal Atlas (2nd Edition)

Those readers familiar with the first edition of The Retinal Atlas will appreciate the comprehensive nature of this publication, and this latest version incorporates retinal images generated by recently developed imaging technology. As the title suggests, this hardcover version is...

OCT in peripheral corneal thinning

This small retrospective study used high resolution optical coherence tomography (OCT) Heidelberg Spectralis to identify features which could determine the underlying aetiology of peripheral corneal thinning. Ten patients were included; five with diagnoses of degenerative peripheral thinning; Terrien’s marginal degeneration...

C-spp corneal consequences

This is a retrospective review of microbiological records of 22 patients, who had presented at the LV Prasad Eye Institute, India, between June 2009 and December 2012. The corneal scrapings were performed in all patients and had yielded significant growth...

Oral omega-3 fatty acid treatment for dry eye in contact lens wearers

This study evaluates the effect of dietary omega-3 fatty acid supplementation of dry eye symptoms, tear film tests, and conjunctival impression cytology in patients with contact lens wear-associated dry eye. In this randomised double-blind, multi-centred trial, contact lens wearers (n=...

Transcriptomic analysis of ocular tissues

Transcriptomics is defined as the analysis of the complete set of RNA transcripts present in a cell under different circumstances, quiescent versus challenge, by microarray analysis. Comparison of transcriptomes identifies genes that are differentially expressed in different cell populations under...

Outcomes after surgery for INS

The purpose of this study was to detail clinical and electrophysical outcomes after extraocular muscle surgery in adults with infantile nystagmus syndrome (INS). This was a single centre prospective case series of 81 patients aged 18-72 years (mean 36); 63%...

Diagnostic accuracy of different keratoconus detection indices of pentacam in paediatric eyes

This is a retrospective study of 432 non-keratoconic eyes compared with 48 eyes with keratoconus (KC) or forme fruste KC (FFKC) in a paediatric population in Cairo, Egypt between December 2013 and October 2018. The authors discuss the rationale of...

Importing iron to the retina

In the retina, iron is particularly critical for the visual phototransduction cascade. In the retinal pigment epithelium (RPE), RPE65 activity leads to 11-cis-retinaldehyde, the photosensitive component of rhodopsin production and iron containing enzymes are necessary for disc replacement in photoreceptor...

Sustained elevation of extracellular ATP in chronic glaucoma

Although adenosine 5′-triphosphate (ATP) release from retinal neurons and astrocytes has been demonstrated in short-term increases in intraocular pressure (IOP); such as in aqueous humor of humans with primary acute angle closure glaucoma, the response in chronic IOP elevation was...