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App detection of leukocoria
This paper outlines ARCELE – Computer Assisted Detection of Leukocoria. This is an iPhone app developed to increase early detection of retinoblastoma by detecting leukocoria. The aim of this study was to determine the use of CRADLE as a screening...
Can the angle of origin of the ophthalmic artery predict embolic trajectory?
A retrospective, comparative case-control study was used to test the hypothesis that a risk factor for retinal versus cerebral infarct is the angular origin of the ophthalmic artery from the internal carotid artery. The study compared one group (n=28) who...
Using lumbar puncture as a diagnostic tool of IIH when the presentation is typical
The authors present the findings of a retrospective observational chart review across three neuro-ophthalmology clinics. Databases at each clinic were searched using inclusion criteria based on established diagnostic criteria for idiopathic intracranial hypertension (IIH). Cases with missing data, atypical findings...
New prognostic model for multiple sclerosis after optic neuritis presentation
The authors present a post-hoc analysis using the publicly available data set from the Optic Neuritis Treatment Trial. The Cox proportional hazards regression models were used to assess for associations between clinical and radiological variables and the development of clinical...
Presenting and diagnostic signs of retinoblastoma
This study revisits the presenting signs of retinoblastoma (RB) in the context of current best practice with respect to diagnosis and assessment of RB. This was a retrospective review of 131 consecutive cases, excluding those with positive family history over...
Could midbrain volume on MRI be used to guide diagnosis of progressive supranuclear palsy?
The authors present a cohort study, of patients with a likely diagnosis of progressive supranuclear palsy (PSP) using a combination of prospective assessment and retrospective review. The cohort comprised of 14 patients; the data for six patients was obtained through...
Intravenous ketorolac during DCR
This study compares pain scores postoperatively between patients that received intravenous ketorolac (IVK) pre, intra or immediately postoperatively and a control group that did not receive it. The authors state that the patients were randomised, however it is not described...
Tocilizumab in Graves’ orbitopathy
This prospective European study looks at the response to tocilizumab in corticosteroid-resistant disease. Tocilizumab (TCZ) is a monoclonal antibody that competitively inhibits IL-6 binding to its receptor. Unlike teprotumumab, the advantage of TCZ is that it is already used within...
Effective contrast ratio as a measure of binocular visual perception
The authors used a binocular phase combination paradigm to quantitatively evaluate and compare the binocular visual perception of normal individuals and patients with different types of strabismus to understand the binocular visual perception of patients with strabismus and evaluate whether...
Attracting workforce to paediatric ophthalmology
This was a survey-based study to address unanswered questions relating to economic and workforce issues in paediatric ophthalmology. The survey comprised 12 questions with yes / no or multiple-choice responses and was circulated to American Association for Pediatric Ophthalmology and...
EEG changes following use of cyclopentolate 1% eye drops
Cycloplegic eye drops may affect the central nervous system. This study reports electroencephalogram (EEG) changes in a cohort of 6–15-year-old children. EEG recordings were taken after placebo and two doses of cyclopentolate 1% in 24 awake children (36 children had...
