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A revolution in modern genetic testing for the clinical management of ocular disease
Recent years have seen a huge increase in our understanding of the genetic factors underlying a wide variety of eye diseases. This has included common conditions such as glaucoma and age-related macular degeneration, as well as those conditions which have...Regulatory drug evaluations and expedited review initiatives: EU and US perspectives
The European Medicines Agency (EMA) and United States Food and Drug Administration (FDA) each conduct independent assessments of benefit-risk profile when evaluating applications to market new or modified medicines, and their respective decision-making is guided by distinct legislation, procedures and...A closer look at the new wave of glaucoma surgery – radical or old school?
Glaucoma is a challenging condition to treat because the exact pathophysiology remains unclear and the only readily modifiable factor is the intraocular pressure (IOP). Additionally, most glaucoma patients are completely asymptomatic, yet are often subjected to lifelong medical therapy. The...In conversation with Dr Robert B Nussenblatt
Dr Robert B Nussenblatt is Chief of the Laboratory of Immunology at the National Eye Institute, an eminent ocular immunologist and an expert in clinical research design and conduct. Describe the success or relevance of the SUN project. The Standardization...Traumatic ‘toy’ gun injury leading to permanent vision loss
Pseudoxanthoma elasticum (PXE) is a progressive, inherited disorder of connective tissue that affects the skin, cardiovascular system and retina. Ocular manifestations of the disease are related to Bruch’s membrane, a thin elastic tissue layer located between the retinal pigment epithelium...Make eye drops a part of your Ramadan routine
Glaucoma UK, the Muslim Council of Britain (MCB), and the British Islamic Medical Association (BIMA) are encouraging Muslims with glaucoma to continue using their medication as prescribed during the holy month to prevent irreversible sight loss.Moorfields to start new retinal detachment clinical trial
Moorfields to start new retinal detachment clinical trial following £1.2 million MRC DPFS grant awarded to UCL and Moorfields Eye Hospital.
RPE atrophy onset in treated nAMD
In this study the authors aim to evaluate the role of various factors for the development of retinal pigment epithelium (RPE) atrophy over a period of five years in patients with nAMD. Fifty-two newly diagnosed nAMD patients with complete absence...Gene therapy for inherited retinal disease: the Manchester Ocular Gene Therapy Group MDT service
The authors describe the process set up in Manchester for the optimum delivery and assessment of a new gene therapy treatment for patients with RPE65 IRD. Inherited retinal dystrophies (IRDs) are the second commonest cause of severe visual impairment in...Capacity-building through the COECSA-RCOphth LINK – linking journals in a training and mentorship programme
The College of Ophthalmology of Central, Eastern and Southern Africa (COECSA) [1] and the Royal College of Ophthalmologists (RCOphth) [2] have a long-standing health partnership through the VISION 2020 LINKS Programme [3,4]. The LINK started a new project in 2019...
Eye Emergencies: The practitioner’s guide (Second Edition)
This book is a comprehensive guide for medical practitioners – nurses or doctors working in the primary care or emergency care setting. It begins with a description of basic anatomy of the eye and the clinical significance of various structures....
