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Protecting retinal ganglion cells

Glaucoma is considered to be a heterogeneous group of conditions giving retinal ganglion cells (RGC) damage. Lowering intraocular pressure (IOP) reduces the risk of progressive RGC loss in glaucoma. Regeneration of the optic nerve has been shown to restore some...

Ophthalmic viscoelastic devices: Useful insights for a novice cataract surgeon

Ophthalmic viscoelastic devices (OVDs) are essential in many different stages of cataract surgery. This article discusses the categories of OVDs and their respective properties, and highlights their uses in different scenarios faced in cataract surgery. Ophthalmic viscoelastic devices are gel-like...

Developing community eye care: the evolution of Wales’ eye care services

In the third in our series about community eye care in the home nations, David O’Sullivan explains how Wales has developed its community eye care services. Since the devolution of healthcare to Wales on 1 July 1999 [1], significant changes...

DR-NET National DR Workshop in Tanzania: Policy, training and technology

Diabetic retinopathy (DR) is a leading cause of moderate to severe visual impairment (VI) and blindness worldwide, posing a significant public health challenge. As the prevalence of diabetes continues to rise globally, particularly in low- and middle-income countries (LMICs), the...

Issues with standard practice: Luer lock syringes in cataract surgery

For a few years, we have worked together with the practice variance surveys to tease out differences in the way we work and to discuss issues that arise. I hope that we have learnt some lessons and reflected on what...

Coming to terms with AI

A machine might be called intelligent if its response to questions could convince a person that it was human, a test proposed by Alan Turing in 1950 [1]. The author considers potential applications of artificial intelligence (AI) using machine learning...

Safety and efficacy of a nurse-led intravitreal injection service using an Precivia® injection assist device

Nurse-led intravitreal injections have become of great importance for busy eye units. In this article, the authors present safety data from five years of a nurse-led service with the use of the Precivia® intravitreal injection assist device. Intravitreal injections of...

Corectopia grading

The authors present a novel corectopia classification system using 28 eyes of 28 patients with or without corectopia. The grading and classification system for corectopia was as follows: (i) Direction of decentration: superior (DecS), superonasal (DecSN), nasal (DecN), inferonasal (DecIN),...

Intracameral antibiotics in cataract surgery: current evidence base

Following on from our recent online survey*, the authors examine the use of intracameral cefuroxime as the standard of care in cataract surgery. Cataract extraction with intraocular lens implantation is one of the most frequently performed surgical procedures in the...

A practical guide to anisocoria

Anisocoria means the presence of difference in the size of the right and left pupils. It is a sign of an abnormality in the efferent pathway. The first question facing the ophthalmologist is to ascertain if anisocoria is present or...

Leading sight loss charity reveals urgent need for change in attitudes towards blind mothers

Ahead of Mothers’ Day, leading sight loss charity the Royal National Institute of Blind People (RNIB) has released research that shows the barriers faced by mothers with sight loss during pregnancy and into their first years of motherhood. This research...

RPTP-σ increases pro-MMP activity in a trabecular meshwork cell line following oxidative stress conditions

This study aims to outline the role of phosphatases in the aqueous drainage system by overexpressing receptor tyrosine phosphatase sigma (RPTP-σ) in a human normal trabecular meshwork cell line and describing its effect on subtypes of matrix metalloproteinases (MMP) and...