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Experimental Eye Research cover image.

Importing iron to the retina

1 October 2017 | | EYE - Vitreo-Retinal
In the retina, iron is particularly critical for the visual phototransduction cascade. In the retinal pigment epithelium (RPE), RPE65 activity leads to 11-cis-retinaldehyde, the photosensitive component of rhodopsin production and iron containing enzymes are necessary for disc replacement in photoreceptor...
Journal of Pediatric Ophthalmology & Strabismus cover image.

Treatment for chronic severe bilateral blepharokeratoconjunctivitis

1 May 2025 | | EYE - Paediatrics, EYE - Strabismus
This study evaluated the efficacy and safety of oral azithromycin treatment combined with topical antibiotics and anti-inflammatory agents in paediatric patients with chronic severe bilateral blepharokeratoconjunctivitis (BKC). The authors recruited 29 consecutive patients (58 eyes) with mean age at diagnosis...
Neuro-ophthalmology front cover image.

Effect of oxygen levels on binocular summation of dark vision

1 December 2014 | | EYE - Neuro-ophthalmology | Binocular summation, dark adaptation, monocular vision, neural summation, probability summation
Previous studies have reported conflicting results on the existence of binocular enhancement of dark vision. This study compares monocular and binocular absolute thresholds of dark adaptation in two different populations (healthy individuals and those with chronic respiratory insufficiency). The study...

Refraction planning in cataract: avoid creating an unhappy patient

1 June 2017 | | EYE - Cataract, EYE - Refractive
“It is much more important to know what sort of a patient has a disease than what sort of a disease a patient has.” William Osler The focus of this paper is the prevention of an unhappy patient following cataract...

Optical coherence tomography – reinventing the eye examination

1 October 2016 | | EYE - Vitreo-Retinal, EYE - Imaging
It has been 25 years since Huang et al. presented the first optical coherence tomography (OCT) images in Science [1]. With vast improvements in OCT technology over the years, it is now possible to acquire high-resolution cross-sectional images of the...

Periocular burns: a literature review of classification, management protocols and outcomes of treatment

1 October 2021 | | EYE - Cornea, EYE - Oculoplastic, EYE - General
The author provides a review of the current literature regarding the principles of classification, management protocols of acute ocular and periocular burns and the role of the burn and oculoplastic surgeon involved in their care. More than two-thirds of facial...

The interpretation and use of ultrasound biomicroscopy (part 1)

1 October 2016 | | EYE - Cornea, EYE - Imaging, EYE - Vitreo-Retinal
Ultrasound Biomicroscopy (UBM) has become increasingly important for the diagnosis of a variety of anterior segment pathologies. Most ophthalmologists are familiar with conventional B-scan ultrasonography techniques, which operate at lower sound frequencies (7.5 to 20MHz). UBM is an ultrasound technique...

Glaucoma-NET: a novel way of improving glaucoma management in sub-Saharan Africa

1 June 2022 | | EYE - Cornea, EYE - General
Background Glaucoma is the second most common cause of blindness worldwide [1]. People with untreated glaucoma suffer from irreversible, progressive loss of sight. The disease is characterised by progressive loss of visual field, with pathological cupping of the optic disc...

Understanding vasoproliferative retinal tumours

4 February 2021 | | EYE - Vitreo-Retinal, EYE - General
Syed Irtiza Ali Shah explores this rare and unusual condition through a fascinating case presentation. Vasoproliferative tumours of the retina (VPTR) are a vascular mass with an associated exudative retinopathy alongside the presence of minimally dilated feeder vessels. This is...

The structure function relationship in glaucoma

1 April 2017 | | EYE - Glaucoma
Chronic open angle glaucoma (COAG) is the second most common cause of blindness worldwide. It is diagnosed on the basis of three clinical signs, raised intraocular pressure (IOP), visual field (VF) defects and structural changes to the optic nerve head...

Congenital and paediatric cataract: Advances in diagnosis and management

4 December 2025 | | EYE - Paediatrics, EYE - Cataract
Congenital and paediatric cataracts are relatively rare, although prevalence varies significantly between countries, influenced by factors such as nutrition, immunisation policy and population genetics [1]. In the UK, around 3–4 of every 10,000 babies are born with cataracts. It’s a...

My ophthalmology elective: East to West

7 May 2026 | | EYE - General
I was fortunate to be able to complete my elective in three different parts of the world: the UK, Vietnam and Pakistan. I spent three weeks at Bristol Eye Hospital (BEH), two weeks at Cho Ray Hospital in Ho Chi...