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Pegcetacoplan: A breakthrough treatment for dry age-related macular degeneration?

12 February 2025 | | EYE - Pathology, EYE - Vitreo-Retinal
Age-related macular degeneration (AMD) is a degenerative condition affecting the macula, the part of the retina responsible for central vision. It is characterised by the presence of drusen and retinal pigment epithelium (RPE) abnormalities in the absence of other macular...

An elective in the land down under

2 April 2026 | | EYE - General
My clinical elective was spent at the Royal Victorian Eye and Ear Hospital (RVEEH) in Melbourne. As Australia’s only specialist tertiary hospital dedicated entirely to eye disease, RVEEH gave me significant exposure to, and enhanced my clinical understanding of, ophthalmology....

MOSUK Annual Meeting 2026

25 February 2026
Medical Ophthalmological Society's 27th Annual Meeting

Discussing treatment modalities for bilateral wet AMD

1 December 2014 | | EYE - Vitreo-Retinal
A 65-year-old lady with bilateral wet AMD and vision of 6/24 comes with an internet search about current therapies. How do you explain the various treatment modalities available? There are two NICE approved treatments for wet age-related macular degeneration (AMD)....
American Journal of Ophthalmology cover image.

Smartphone ophthalmoscopy vs. slit-lamp biomicroscopy in diabetic retinopathy

1 June 2016 | | EYE - Vitreo-Retinal
In this prospective, comparative, clinical study the authors’ aim was to assess the reliability and accuracy of smartphone ophthalmoscopy as compared with standard slit-lamp biomicroscopy in the grading of diabetic retinopathy. One hundred and twenty consecutive, new, diabetic patients underwent...

Corneal crosslinking in pellucid marginal degeneration

1 April 2020 | | EYE - Cornea, EYE - General
Fourteen studies were included in this first review examining the use of corneal-crosslinking (CXL) to treat pellucid marginal degeneration (PMD). PMD is a bilateral, non-inflammatory corneal thinning disorder characterised by inferior peripheral corneal thinning 1-3mm from the limbus in the...
Journal of Pediatric Ophthalmology & Strabismus cover image.

Retinoblastoma risk factors for recurrence

7 April 2021 | | EYE - Paediatrics, EYE - Strabismus
This study evaluates risk factors for local tumour recurrence of main solid tumour, subretinal seed, vitreous seed and new tumour formation in eyes with retinoblastoma (RB) management with primary chemotherapy over 20 years of follow-up. The study included 960 eyes...

Cavernous sinus syndrome

4 February 2021 | | EYE - Neuro-ophthalmology, EYE - General
Anatomically the cavernous sinus is a plexus of multiple veins that are connected and within this plexus there are several important vascular and neurological structures. These include cranial nerves III, IV, V1 (and sometimes V2), VI as well as the...

Oculogyric crisis with B12 deficiency

1 June 2022 | | EYE - Neuro-ophthalmology, EYE - Imaging, EYE - General
An oculogyric crisis (OGC) is a dystonic movement disorder of the eyes which can last from seconds to hours. Although there is no published diagnostic criteria for OGC, typically the onset is acute, and it is characterised by conjugate upward...

Oculoplastics: an evolving specialty

1 August 2015 | | EYE - Oculoplastic, EYE - Orbit
Consultant Ophthalmic and Oculoplastic Surgeon Raman Malhotra provides an insight into this increasingly popular subspecialty of ophthalmology. Oculoplastic surgery refers to plastic, reconstructive and aesthetic surgery of the eyelids, the surrounding facial areas, orbits and lacrimal system. Its scope has...

Feb/Mar 2016 Quiz 2

1 February 2016 | | EYE - Cataract, EYE - Cornea, EYE - Glaucoma, EYE - Imaging, EYE - Neuro-ophthalmology, EYE - Oculoplastic, EYE - Oncology, EYE - Orbit, EYE - Paediatrics, EYE - Pathology, EYE - Refractive, EYE - Strabismus, EYE - Vitreo-Retinal, EYE - General
History A 30-year-old male presents with a phthisical left eye and undergoes enucleation. He has some lesions in his right eye that are under ophthalmic surveillance. Figure 1 is a low power of the enucleation. Figures 2, 3 and 4...

Refraction planning in cataract: avoid creating an unhappy patient

1 June 2017 | | EYE - Cataract, EYE - Refractive
“It is much more important to know what sort of a patient has a disease than what sort of a disease a patient has.” William Osler The focus of this paper is the prevention of an unhappy patient following cataract...