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Gene therapy for inherited retinal disease: the Manchester Ocular Gene Therapy Group MDT service

The authors describe the process set up in Manchester for the optimum delivery and assessment of a new gene therapy treatment for patients with RPE65 IRD. Inherited retinal dystrophies (IRDs) are the second commonest cause of severe visual impairment in...

Streamlining cataract lists: how are you managing it?

Mr Jonathan Ross, in conversation with Ms Bita Manzouri, provides a personal perspective on challenges and opportunities shaping the future of cataract surgery services across the hospital eye service. Redesigning cataract pathways in response to COVID-19 Bita Manzouri: Over the...

Blame the lens – not its position – in refractive surprise

Aetiology of postoperative refractive surprise Weber coined the term “wrong eye, wrong intraocular lens, wrong patient” in 2008 as an aide memoir of major factors believed to underlie refractive surprise – defined as a significant unintended difference between dioptric refraction...

Real world data of post-IVT endophthalmitis, from a nurse-delivered intravitreal injection service

Introduction Intravitreal injection of neutralising anti-vascular endothelial growth factor (VEGF) antibody was licenced more than a decade ago, and over the years there has been proportionate increase in the number of intravitreal injections [1]. Injection of a therapeutic agent through...

Spotlight: The Community Eye Health Journal

In many low-income settings, where vision loss is greatest, eyecare is hampered by shortages in trained health workers. In sub-Saharan Africa, there are fewer than five ophthalmologists per million population, compared to over 70 per million in high-income countries. Eyecare...

The ROP Network: a south-south collaboration to improve care for premature babies

Retinopathy of prematurity (ROP) is a disorder of the immature preterm retina and a leading cause of preventable, irreversible blindness in children. There are 15 million preterm births annually, and over 32,000 neonates became blind from ROP in 2010 [1]....

Second sight: Ian McKinley

I have always been captivated by a true-life story demonstrating the human spirit of triumph over adversity. For me, one of the most memorable sportsmen overcoming an injury has always been the mountaineer Joe Simpson and his tale of survival...

Strabismus and ocular motility, demystified

I am a former orthoptist, now trained in medicine and working as a foundation doctor. In my previous work, I was frequently approached by ophthalmology trainees eager for guidance with strabismus and ocular motility. Drawing on my clinical experience, I...

Part 2: the Arclight Device: frugal imaging for eyecare

In this three-part series (Click here for Part 1 and here for Part 3) Andrew Blaikie and his team explore the role and application of the Arclight Device in Imaging of the Eye. There are many different types of ophthalmic...

Mucormycosis: In conversation with Dr Deepak Haldipur and Dr Aditya Moorthy

COVID-19 has ravaged the world in the past 18 months. The second wave in many countries was deadlier than the first. Mucormycosis, infamously labelled ‘the black fungus’ has affected some countries, such as India, in epidemic proportions within this COVID...

General purpose AI: Transitioning from high performance in highly curated settings to useful applications in ophthalmology

Artificial intelligence (AI) may be understood as the ability of machines to perform tasks which otherwise require human perception, reasoning, or learning. With the advent of deep learning, AI has achieved remarkable results across a wide range of medical tasks...