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Crystalline keratopathy in monoclonal gammopathy of undetermined significance

Monoclonal gammopathies encompass a group of plasma cell disorders characterised by the excessive production of abnormal monoclonal immunoglobulins in the bloodstream [1]. This category includes multiple myeloma, monoclonal gammopathy of undetermined significance (MGUS), amyloidosis and other lymphoproliferative disorders. Monoclonal gammopathy...

Corneal hysteresis: An emerging biomarker in the management of glaucoma

Corneal hysteresis (CH) is gaining recognition as a valuable parameter in the management of glaucoma. Corneal hysteresis is defined as the difference between the inward and outward pressure responses of the cornea during deformation. This measurement reflects the viscoelastic properties...

Infection prevention and control through a VISION 2020 LINK between Mombasa and Southampton

The authors share how a partnership between Mombasa and Southampton has enabled Kenyan healthcare professionals from four institutions to innovate and work as a group to improve infection prevention and control. Infection prevention and control (IPC) is a cornerstone of...

The Makassar-Dundee VISION 2020 LINK: a tale of two cities and two trainees

A resident’s view from Makassar My name is Hendra Kusuma, a final year resident (registrar) in the ophthalmology department at Hasanuddin University in Makassar, Indonesia. We have had a VISION 2020 LINK with Dundee (coordinated at the UK end by...

The paediatric cataract: an overview of the embryology and pathophysiology

In the first of the two articles (see Part 2 here) on paediatric cataracts, Samuel Aryee reviews the aetiology of this condition. Cataracts arise from opacification of the natural transparent lens, which can cause partial or total blindness. Although the...

Proning and the pandemic - ocular complications seen in critical care

Priyanka Sanghi and her co-authors explore the ocular complications seen in critical care units throughout the country as we treat patients through this challenging time. The SARS-Cov-2 (COVID-19) pandemic has placed the NHS and critical care services under immense strain,...

Is it NAION… Now what?

Case presentation We present the case and discussion of a 46-year-old Caucasian male who complained of immediate reduced vision following complicated neck dissection including a total laryngopharyngectomy, free flap reconstruction for a T4N3 squamous cell carcinoma (SCC) of the left...

Regulatory drug evaluations and expedited review initiatives: EU and US perspectives

The European Medicines Agency (EMA) and United States Food and Drug Administration (FDA) each conduct independent assessments of benefit-risk profile when evaluating applications to market new or modified medicines, and their respective decision-making is guided by distinct legislation, procedures and...

The ‘theatre of the mind’: Charles Bonnet Syndrome and Esme’s Umbrella

The founder of Esme’s Umbrella shares her experience with the poorly understood condition Charles Bonnet Syndrome and the creation of the campaign. Many years ago, when I was a young actress, I was in an American play called ‘Butterflies are...

Thyroid eye disease

Thyroid eye disease (TED) is an autoimmune condition with a spectrum of signs and symptoms, usually associated with Graves’ hyperthyroidism. The diagnosis is based on history and physical examination but there are further investigations that can aid diagnosis if unclear....

My Top Five: Foundation year 3 jobs for prospective ophthalmology candidates

Ophthalmology specialist training (OST) is a fantastic career option, however, it is also a highly competitive specialty. There was a gradual rise in competition ratios in recent years: 3.24 (2019), 5.73 (2020), and 6.80 (2021) [1]. Many choose to pursue...

The impact of obstructive sleep apnoea monitoring functionality on smartwatches: a new frontier for ophthalmologists

Dawn of a new era in wearable technology? Smartwatches have really stepped up their game and have evolved from telling time to keeping an eye on our health. In February 2024, the United States Food and Drug Administration (FDA) gave...