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Visually Impaired Creators perform at Edinburgh Fringe

What’s it like to see a show… without seeing it?

The role of virtual Rb-NET Multidisciplinary Team meetings in the management of children with retinoblastoma in low- and middle-income countries

A selection of participants in an MDT meeting with Uganda. In 2017 the LINKS Programme developed a new network of LINKS to support and coordinate action against retinoblastoma (Rb) in response to requests from low- and middle-income countries (LMICs), called...

Treatment of Sjogren’s Syndrome dry eye in mouse model

Sjogren’s syndrome (SS) is a chronic autoimmune disease characterised by inflammation of the exocrine glands, specifically the salivary and lacrimal glands that produce saliva and tears, respectively. The immune-mediated attack on the salivary and lacrimal glands leads to the development...

How to achieve 1% solution of Lissamine green

Lissamine green (LG) concentration of 1% is clinically effective in the diagnosis of ocular surface disease. LG is now commercially available only in a form of dye-impregnated strips, whose concentration is insufficient. This study examined how to achieve 1% concentration...

Differential inhibition of EAU by CTLA4 and IL-6

Cytotoxic T lymphocyte antigen-4 (CTLA4) binds both CD80 and Cd86 and inhibits T lymphocyte activation via CD28. Il-6 is a pleiotropic cytokine that has been associated with many autoimmune conditions including uveitis. Blockade of these molecules by either CTLA4-Ig, a...

Slanted MR surgery for convergence excess ET

The authors aimed to evaluate the surgical outcomes of bilateral slanted recessions of the medial rectus (MR) muscles in patients with convergence excess esotropia (ET). This retrospective study included 16 patients with a mean age at surgery of 5.6 ±3.05...

Effect of laser wavelength on delivering effective burns through opaque lens using pattern scan laser

Panretinal photocoagulation (PRP) has been used in the treatment of various retinal disorders for many decades. Conventional single-spot lasers take quite some time to do with significantly higher pain, anxiety and photophobia when compared to the pattern scan laser (PSL)....

Cost-effectiveness of femtosecond cataract surgery

Femtosecond laser-assisted cataract surgery has become increasingly popular due to the reported benefits of increasing precision and reproducibility of capsulorrhexis, less power and manipulation required during phacoemulsification, better corneal wound architecture, and the ability to place precise arcuate keratotomy incisions...

Features of AMD treatment non-responders

This is a retrospective consecutive case series of 365 eyes with age-related macular degeneration (AMD) who had three monthly intravitreal aflibercept treatments for at least 12 months. Responders were defined as complete resolution of exudation, intraretinal oedema, subretinal fluid, pigment...

Surgical treatment for monocular elevation deficit

Type 1 monocular elevation deficiency is a restrictive form identified by positive results on forced duction testing in elevation, normal elevation forced generation test, elevation of saccadic velocity and absence of poor Bell’s phenomenon. The authors aimed to evaluate the...

Surgery for third nerve palsy (2019)

The authors present a new technique for split muscle medial transposition surgery of the lateral rectus plus union with the distal split stump of the medial rectus. This increases the length of the contracted lateral rectus through the addition of...

Using small amplitude saccades to assess saccadic velocity

Saccades are a key component in the assessment and diagnosis of neuro-ophthalmological disorders. Clinicians are typically taught to use large amplitude saccades (LAS) of at least 20 degrees to assess saccadic velocity. It has been suggested, however, that small amplitude...