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MicroRNA mediate retinoblastoma signal transduction
MicroRNAs (miR) are small non-coding single-stranded RNA molecules, normally 22 nucleotides long. There is a large family of miR that control protein expression by binding to mRNAs, leading to their degradation. One important role of miR is in tumours where...The art of ophthalmic simulations
For Dec/Jan 2024, I got in touch with Nicky Webster, a Principal 3D Artist at FundamentalVR (https://fundamentalsurgery.com). Nicky is also a registered medical illustrator, healthcare scientist and medical photographer. With over 18 years of experience working in various disciplines within...
Scheimpflug images and graft rejection
This study aimed to assess corneal changes using 360-degree Scheimpflug images and pachymetry readings to outline screening parameters, which define graft rejection. Seventeen eyes of 16 patients developed clinically manifest allograft rejection two to 42 months after surgery – those...Collaborating across the Caribbean to tackle diabetic retinopathy
The VISION 2020 LINKS Programme has been running since 2004, with a focus on improving the quality and quantity of eye care training in low-income countries [1]. In 2014, the Diabetic Retinopathy Network (DR-NET) was established [2]. This is a...The Global Vision Database
The overall goal of the Global Vision Database (GVD) [1] is to develop and deploy new and improved evidence on the prevalence of blindness and vision impairment (VI) globally. It is a repository which allows us to assess the causes...Laser corneal refractive procedures – a review
Evolution of refractive surgery stays true to the quote of Theodore Roosevelt: “The more you know about the past, the better prepared you are for the future.” Refractive surgery is an evolving field, which thanks modern technologies for refining ideas...
The effect of orbital decompression on upper eyelid retraction
This is a systematic review and meta-analysis on whether there is a change in upper lid retraction following orbital decompression. Traditional teaching states that the order of surgery for thyroid eye disease should be decompression firstly, followed by squint surgery...
Strabismus detection by Plusoptix S08
In this study the authors evaluate the accuracy and sensitivity of the Plusoptix S08 photoscreener in detecting strabismus problems in 83 patients aged from six months to 40 years (mean 105 months). A pass was achieved for 25 patients and...
Use of bovine pericardium for tendon elongation
A retrospective analysis was conducted on all patients treated in one centre with tendon elongation using bovine pericardium (BP) to examine outcomes and long-term safety. The study included 60 patients; 27 unilateral and 33 bilateral cases. Follow-up of one to...
Medial rectus recessions for ACE
The goals of this study were to describe the clinical features of acute concomitant esotropia (ACE), analyse the surgical results and evaluate correlations with clinical variables. This was a retrospective study of 15 patients with mean age of 39.2±10.7 years;...
Combined recession surgery with Bupivacaine injection
The aim of this study was to evaluate the amount of correction of sensory strabismus with Bupivacaine injection combined with antagonist muscle recession. This was a prospective study of nine patients aged 43.5 ±12.3 years; six males and three females....
