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Regulatory drug evaluations and expedited review initiatives: EU and US perspectives
The European Medicines Agency (EMA) and United States Food and Drug Administration (FDA) each conduct independent assessments of benefit-risk profile when evaluating applications to market new or modified medicines, and their respective decision-making is guided by distinct legislation, procedures and...Doing a systematic review: a users’ guide for foundation doctors
Research is increasingly important for junior doctors and systematic reviews (SRs) are a great place to start. Carrying out an SR can help a doctor demonstrate commitment to a specialty, develop research skills and get results quickly. This article aims...The curse of the college museum
David Greig lecture notebook. Courtesy of Dr Jacqueline Cahif, College Archivist, Royal College of Surgeons of Edinburgh. As sure as the inevitability of death and taxes, the hidden stories of past events will intermittently rise to the surface like oil...CooperVision announces UK&I OptiStudent™ award winner
The end of June saw the final of the UK&I OptiStudent™ Awards, an annual competition for optometry students across Europe, organised by global contact lens manufacturer, CooperVision. Representing Cardiff University, third year optometry student, Cherilyn Tan, was announced as this...Optic nerve swelling – your survival guide (part 1)
Assessment of optic nerve appearance and functions is a daily routine in neuro-ophthalmology. Following a recent high profile court case there has been a significant increase in the amount of referral to ophthalmology departments to assess the optic nerve and...The role of spectral-domain OCT RNFL in revealing a pituitary adenoma with atypical visual fields
Pituitary adenomas classically cause bitemporal hemianopia by compressing the optic chiasm. However, in some cases, the pattern of visual field loss may be atypical and mimic homonymous hemianopia, depending on the direction and extent of tumour expansion. Spectral-domain optical coherence...The VISION 2020 LINKS Programme: Cascading leadership training in Calabar, Nigeria
The VISION 2020 LINKS Programme has initiated ‘LEAD FORWARD’, an innovative leadership development project incorporating a commitment to cascade training and participate in achievable quality or service improvement projects. The project provides opportunities to apply leadership skills in practice as...
Fifteen-year results of phakic artisan IOL for hyperopia correction
This retrospective review of a cohort of 61 eyes from 32 patients offers long-term results for phakic Artisan (Ophtec BV) iris-fixated phakic IOL (IF-pIOL). The mean age at surgery was 41.6 years with a range of 25-59 years. Refractive outcomes...
Mid-term evaluation of the new Glaukos iStent
This is a prospective non-randomised interventional study to assess the efficacy and safety of the Glaukos GTS-400 iStent combined with cataract surgery. The patients enrolled in the study had cataract and primary open angle glaucoma, pseudoexfoliation glaucoma or ocular hypertension....My work experience with Great Ormond Street Hospital Young Persons’ Advisory Group for Research
For my school work experience I had the amazing opportunity to attend and work with the Great Ormond Street Hospital (GOSH) Young Persons’ Advisory Group for research (YPAG) (Figure 1). The GOSH YPAG is a group of young people aged...Tackling diabetic retinopathy globally through the VISION 2020 LINKS Diabetic Retinopathy Network
It is abundantly clear that the burden of diabetes is rapidly increasing, as there are now 415 million adults with diabetes in the world, with a projected rise to 642 million by 2040 [1]. This equates to 1 in 10...
