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Incomplete teprotumumab treatment for thyroid eye disease

This is a multi-centre retrospective analysis of clinical outcomes in patients who were on teprotumumab for thyroid eye disease but had the usual regime of eight infusions, three weeks apart, interrupted due to COVID-19. Manufacturing was suspended between Dec 2020...

Eyes on Rwanda: Lessons from an international ophthalmology experience

On the 26 February 2025, I travelled to Rwanda on the invitation of a former Belfast trainee, Michael Mikhail. Michael is now one of only two vitreoretinal (VR) surgeons in Rwanda, a country with a population of 14 million. Born...

What's trending Jun/Jul 2025

A round-up of the eye-related hot topics that have been trending on social media over the last few weeks. #Inspiration #FlyingEyeHospital It was with great sadness that I read about the passing of Dr David Paton at the age of...

Capsular tension rings to reduce refractive shift

The study group aimed to determine whether the use of a capsular tension ring (CTR) can increase refractive stability in patients with implantation of two different trifocal intraocular lenses. This was a prospective, consecutive series of eyes which underwent refractive...

The Syrian Ophthalmologists Initiative (SOI): A lifeline to the future of ophthalmology in Syria

Syria, a nation with over 22 million people, has faced more than a decade of conflict that has severely impacted its healthcare infrastructure. Medical training has become fragmented, with many doctors lacking access to structured postgraduate education and essential clinical...

DMEK vs. UT-DSAEK: has the debate been finally concluded?

In recent years the surgical treatment of corneal endothelial dystrophy has progressed tremendously. Descemet’s membrane endothelial keratoplasty (DMEK) is the newest iteration in the line of rapid surgical advances that has taken place. However, the previously accepted gold standard prior...

‘At risk’ corneas are more easily identified with SCORE

Risk assessment of post-LASIK corneal ectasia in refractive surgery patients is now a more exact, objective, evaluation thanks to the work of Heidelberg Engineering and a leading research partner in Paris.

The paediatric cataract: an overview of the embryology and pathophysiology

In the first of the two articles (see Part 2 here) on paediatric cataracts, Samuel Aryee reviews the aetiology of this condition. Cataracts arise from opacification of the natural transparent lens, which can cause partial or total blindness. Although the...

Intravitreal injections delivered by ophthalmic clinical nurse specialists

Intravitreal injections of the anti-vascular endothelial growth factor (anti-VEGF) agent ranibizumab, for the treatment of wet age-related macular degeneration (AMD) was approved by National Institute for Health & Care Excellence (NICE) in 2008 [1]. The Manchester Royal Eye Hospital (MREH),...

Could the sclera be key to glaucoma?

The glaucomas are a group of conditions characterised by optic neuropathy and associated visual field defects. Of these, chronic open-angle glaucoma (COAG) – diagnosed on the basis of progressive structural changes to the optic nerve head (ONH) and nerve fibre...

Oct/Nov 2014 Quiz

History 12-year-old cattle herder in Bangladesh. Loss of vision right eye – over 2/12 to no perception of light (NPL). B-scan showed choroidal thickening. Suspected to be choroidal ‘tumour’. Enucleated. Figure 1. Figure 2. Figure 3. Figure 4. Figure 5....

Diabetic retinopathy screening in Belize: a country’s journey towards reducing blindness from DR

The rise of diabetes mellitus (DM) and its complications is a public health concern in the Caribbean. The Caribbean Diabetic Retinopathy (DR) Programme, managed by the London School of Hygiene & Tropical Medicine (LSHTM) and funded by the Queen Elizabeth...