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2190 results found

Confocal microscopy and corneal graft rejection

Forty-five patients following penetrating keratoplasty (PK) were examined with the HRT III Rostock Cornea Module confocal microscope at various points after their surgery for two years. Activated keratocytes (AKs) were counted manually and their mean number evaluated. A pattern was...

Fixation disparity measurement

The authors evaluate different procedures looking at point zero, fixation disparity (FD) and motor fusion amplitude in order to calibrate the measurement of FD with Ogle’s apparatus with the overall goal to create a standardised measurement of the FD curve...

Correlation between peak intraocular pressure following water drinking test and pulsed methylprednisolone therapy

Steroids have long been known to cause increased intraocular pressures (IOP) in susceptible patients. Intravenous methylprednisolone is used to treat many rheumatological conditions and one of the risks is raised intraocular pressure. It would be useful to find patients at...

A prospective trial of adjuvant therapy for high-risk melanoma

Patients diagnosed with iris, ciliary body or choroidal melanoma of high-risk tumour cytogenetics (monosomy 3>/= 20% of cells), were treated with adjuvant low-dose dacarbacine (DTIC) and interferon –alpha-2b (IFNA-2b), following primary treatment (enucleation, brachytherapy or resection). DTIC was given intravenously...

How a paediatric population presented with diplopia

The authors present the results of a retrospective records review of 244 children presenting with diplopia over a three-year period. The majority of cases presented to paediatric ophthalmology clinic; other routes of presentation included eye casualty, neuro-ophthalmology or another eye...

Management options for microphthalmia with orbital cyst with / without visual potential

The authors present six cases (seven eyes) of congenital microphthalmia and orbital cyst. These cases were newborn mainly with one aged 20 years. There were four females and two males and two of seven eyes had a visual potential of...

Normative dimensions of the lacrimal gland

This article looks at the normative dimensions of the lacrimal gland in the axial and coronal plane on fat-suppressed T1 weighted contrast-enhanced magnetic resonance imaging (MRI). Previous data on this subject has come from computed tomography (CT). MRI is known...

Vigabatrin-induced retinal toxicity detected by 30Hz ERG

The purpose of this study was to assess the role of 30Hz flicker electroretinogram (ERG) as a marker for measuring changes in visual function over time in children receiving vigabatrin. This was an observational study of 11 children with mean...

Aug/Sep 2019 Quiz

History A 73-year-old female patient was referred for rapid growth of two new lesions on the face. She had past medical history of systemic lymphoma. On examination, there was a palpable mass over the left superior orbital region and the...

How to survive the fluorescein round

One of the highlights of the medical retina fellowship programme at Moorfields is the Tuesday morning 8am fluorescein round. It is both exhilarating and terrifying. Exhilarating because they are slick presentations of the most interesting cases that each of the...

What's trending Oct/Nov 2019

#probeyeotic #eyeballbugs #microbiome The human microbiome usually conjures up images of the gastrointestinal tract and yoghurt containing good bacteria. However, research suggests that the ocular mucosa is home to a unique microbe collection, with important immunological functional properties [1]. This...

From the Editors: Back in the habit!

Recently I spoke at an ophthalmic conference in London. It was amazing to be back amongst friends and colleagues in person again, to learn and share with one another. I also took the opportunity to stay on for a few...