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Simulated ocular surgery
See also Simulated ocular surgery - strabismus surgery and Simulated ocular surgery: pars plana vitrectomy and scleral buckling surgery This is the first of a series of articles that will have three aims. Firstly, to demonstrate why simulated ocular surgery...Ophthalmology elective in China
Wandering through the bustling streets of Zhejiang, China, immersed in the harmonious blend of modernity and tradition, I made my way to the Eye Centre of the Second Affiliated Hospital, Zhejiang University College of Medicine. The aroma of traditional Chinese...Exploiting nature’s randomised trials of eye disease
Confounding and reverse causation in observational ophthalmic epidemiology Traditional observational studies are inherently limited in establishing a causal effect of an exposure on an outcome of interest. One fundamental limitation is confounding, whereby causation is incorrectly attributed to a third...
RTP801 as a neuroprotective and axon regenerative treatment
This paper describes the neuroprotective and axon regenerative effects of siRTP801, which is a translatable small-interfering RNA (siRNA) targeting mTOR negative regulator; RTP801, through in-vivo and in-vitro models. In-vivo studies involved an optic nerve crush rat model with intravitreal injections...
Outcomes of cataract surgery in patients with uveitis
This is a systematic, evidence-based literature review and meta-analysis, looking at the visual outcomes (vision 20/40 or better) of cataract surgery in uveitic eyes. The authors searched MEDLINE, EMBASE, CINHAL and CENTRAL, including English language and human studies only. They...
Customised orbital implants
This is a literature review of the outcomes of orbital fracture repairs using custom-made orbital implants. Customised implants were manufactured in one of three ways, all using a 3D printer; manual moulding of an implant based on a 3D-printed model...
Submacular haemorrhage associated with nAMD: A meta-analysis and meta-regression on use of tPA and anti-VEGFs
The aim of this study was to evaluate the efficacy of a combination of tPA and anti-VEGF in the treatment of submacular haemorrhage (SMH) associated with neovascular age-related macular degeneration (nAMD). A systematic review meta-analysis following PRISMA guidelines, focusing on...
Efficacy of BT as a treatment for cranial nerve palsy in acute and chronic cases
The authors performed a meta-analysis of all patients’ treatment with botulinum toxin (BT) for cranial nerve palsy (CNP) to determine the efficacy of BT in the treatment of CNP due to a variety of causes. The search identified 1129 articles...
Junior doctors in emergency departments lack confidence when managing ophthalmic emergencies
This systematic review assessed the confidence of doctors in the UK working in emergency departments (EDs) to manage ophthalmic emergencies, with secondary outcomes looking at doctor’s confidence in performing fundoscopy and using the slit-lamp, and training received in the ED....Sexually transmitted conjunctivitis – the REALLY sticky eye
Let’s face it, patients with conjunctivitis don’t always produce the most stimulating consultations and most of the time we can manage them in auto-pilot. The prospect of delving into such a patient’s sexual history is not overly appealing, but this...
