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Progressive myelination of the retinal nerve fibre layer: Acquired or incidental?

*Co-first authors.Myelinated retinal nerve fibres are retinal nerve fibres encased by a myelin sheath, located anterior to the lamina cribrosa [1]. First described by Virchow in 1856, a myelinated retinal nerve fibre layer (RNFL) appears as a whitish, feathery patch...

RaScaL Study

The RaScaL study was a six month, single-centre, controlled, prospective phase I/II study in which subjects with diabetic macular oedema (DME) and associated peripheral nonperfusion on ultrawide-field fluorescein angiography (UWFA) were randomised to: (1) study arm: ranibizumab (0.5 mg) injection...

An update on inherited retinal disorders (part 1) – overview and assessment of inherited retinal disease

Part 2 of this topic can be found here Inherited Retinal Disease (IRD) is the leading cause of blindness certification in the working age population (age 16-64 years) in England and Wales and the second most common in childhood [1]....

Volunteer abroad: the Khmer Sight Foundation

A team of volunteers describe their experiences of working with the Khmer Sight Foundation in Cambodia. Cambodia has a population of 15 million people, of whom an estimated 300,000 are blind. This figure is increasing by 10,000 each year. Three-quarters...

Zeiss field machines, public Wi-Fi risks and IoT scanning

End of support for old field machines Zeiss have recently announced that they are withdrawing support contracts for many of their older 7 series Humphrey Field Analysers (HFAs) in November 2017. They have confirmed maintenance contracts can continue, but repairs...

How to diagnose and treat Acanthamoeba keratitis

Corneal ulceration caused by Acanthamoeba is on the rise, and recent publications indicate an outbreak in the UK over the last few years [1]. Since Acanthamoeba keratitis often presents with atypical features, diagnosis from slit-lamp examination alone can often be...

From the Editors: Back in the habit!

Recently I spoke at an ophthalmic conference in London. It was amazing to be back amongst friends and colleagues in person again, to learn and share with one another. I also took the opportunity to stay on for a few...

Headaches in ophthalmology (part 2)

Ophthalmologists see a large number of patients with headaches or facial pain in the ophthalmic outpatient clinics or in emergency clinics. Over two articles, I will discuss several causes of headaches, ocular manifestations and proposed management and referral options. It...

Moorfields Eye Hospital, UCL Institute of Ophthalmology and Topcon Healthcare, Inc. launch Cascader Limited to advance AI-driven eyecare and Oculomics

Moorfields Eye Hospital NHS Foundation Trust, the UCL Institute of Ophthalmology (IoO), and Topcon Healthcare today announced the launch of Cascader Limited, a new medical technology company that aims to transform the detection and management of eye disease through artificial...

Landmark dataset to accelerate research on anterior segment eye disease

Diseases affecting the anterior segment, the front part of the eye, are among the leading causes of visual impairment and blindness globally, yet few large-scale datasets have been available for these conditions. In response, clinical researchers at Moorfields Eye Hospital...

The 12 Days of UKISCRS: Celebrating the 75th Anniversary of the IOL

On the three days of UKISCRS, my IOL gave to me… Sparkles and great company, Trainees and mentors shaping who I’ll be, Insightful talks and memories to cherish endlessly! I had the privilege of attending the inaugural 48th Annual UKISCRS...

COECSA-RCOphth LINK Partnership: Knowledge sharing from the conference scene

Nick Astbury caught up with President of the Ophthalmology Society of Uganda (OSU), Faith Nakubulwa, and Angela Birungi, Scientific Chair for OSU, to discuss their key learnings taken away from the RCOphth 2026. Nick Astbury (NA): One of the key...