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Another plant-based remedy for the eye?
Simerdip Kaur takes a look at the latest ophthalmology-related news stories and asks which are based on facts and which are ‘fake news’. Headline: Another plant-based remedy for the eye? What do the nicknames Mary Jane, tea, and 420 all...NICE drugs: an update on what’s good to go
Treatment options recommended by the National Institute for Health and Care Excellence (NICE) must be readily available for use in the NHS of England and Wales. This article provides an overview of recent guidance from NICE and summary advice issued...Adaptive optics imaging: resolving single cells in the living eye
The human retina is unique in the central nervous system (CNS) in that it can be directly visualised non-invasively. Technological advances of several imaging modalities, including optical coherence tomography (OCT), multichannel scanning laser ophthalmoscopy (SLO) and fundus photography, have afforded...
Ptosis procedure compared to upper blepharoplasty on dry eye syndrome
In this prospective, comparative case series, the authors compare the effect of combined blepharoplasty and Muller muscle conjunctival resection (MMCR) to an upper blepharoplasty in dry eye syndrome. The study was approved by the local institutional review board and participants...Birmingham Neuro-Ophthalmology Afferent Course 2027
Objective: The aim is to review the physiology and the pathology of optic nerve disorders. The course is aimed at ophthalmologists, neurologists, medics and orthoptists of all grades. It will be of value to those preparing for exams or refreshing...
Pain control during orbital implant surgery
This is a study based on existing evidence that pre-emptive pain control has advantages over traditional post-surgical analgesia. The authors compared pain scores in three groups of randomly assigned and masked patients all undergoing orbital implant surgery under general anaesthesia...
Intravitreal afibercept and ranibizumab for PCV
This is a retrospective, interventional series comprising 98 eyes with polypidal choroidal vasculopathy (PCV) with the aim of comparing treatments with afibercept and ranibizumab, highlighting any differences in their efficacy. Case notes and imaging (FFA / ICG / OCT) were...
Trial of low-concentration bimatoprost and timolol eye gel versus higher concentrations
This is an international, multicentre, randomised, parallel group, investigator-masked study of 554 patients, having insufficient control of intraocular pressure (IOP) with a first-line monotherapy and requiring dual therapy. Two hundred and eighty patients were randomised to receive low concentration (BTFCEG...
Treatment of Sjogren’s Syndrome dry eye in mouse model
Sjogren’s syndrome (SS) is a chronic autoimmune disease characterised by inflammation of the exocrine glands, specifically the salivary and lacrimal glands that produce saliva and tears, respectively. The immune-mediated attack on the salivary and lacrimal glands leads to the development...
How to achieve 1% solution of Lissamine green
Lissamine green (LG) concentration of 1% is clinically effective in the diagnosis of ocular surface disease. LG is now commercially available only in a form of dye-impregnated strips, whose concentration is insufficient. This study examined how to achieve 1% concentration...
Differential inhibition of EAU by CTLA4 and IL-6
Cytotoxic T lymphocyte antigen-4 (CTLA4) binds both CD80 and Cd86 and inhibits T lymphocyte activation via CD28. Il-6 is a pleiotropic cytokine that has been associated with many autoimmune conditions including uveitis. Blockade of these molecules by either CTLA4-Ig, a...
