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Genetic profiling for personalised healthcare solutions in AMD – an update

Age-related macular degeneration (AMD) is a multifactorial condition influenced by genetics and lifestyle factors (Table 1). This article outlines several recent advances in AMD genetics, as well as evolving therapeutic concepts and established practical measures for the treatment and /...

Diary from my elective: a Parisian experience

The author explains how a research institute’s dedication to multidisciplinary collaboration helped him to discover a passion for academic ophthalmology. The elective aspect to the final year of a medical degree, through its change of scenery and immersion into another...

Unexpected diagnoses – stroke in children and homonymous hemianopia

We present the case of a 12-year-old child presenting with a few days history of left-sided visual loss. Upon further investigation with magnetic resonance imaging (MRI) she was unexpectedly diagnosed with a right-sided chronic posterior cerebral arterial territory infarct, causing...

An update on idiopathic intracranial hypertension

The incidence of Idiopathic intracranial hypertension (IIH) is increasing, likely in line with the worldwide epidemic of obesity. To date, there have been revisions in the terminology used and diagnostic criteria for IIH; these recognise the need to exclude secondary...

Like a moth to AC flare: CMV-associated hypertensive anterior uveitis

Hypertensive anterior uveitis can present a diagnostic challenge to clinicians working in emergency eye departments. While prompt initial control of intraocular pressure (IOP) and inflammation is essential, elucidating the underlying aetiology is critical for long-term visual outcomes. When there is...

Strengthening eye care services in Botswana through the Botswana-Addenbrooke’s Abroad VISION 2020 LINK

The VISION 2020 LINK between Botswana and Addenbrooke’s Abroad has been running for 10 years. With support from the VISION 2020 LINKS Programme two-way exchange visits were undertaken leading to the formation of the first formal international partnership under Addenbrooke’s...

ChatGPT cannot pass FRCOphth examinations: implications for ophthalmology and large language model artificial intelligence

Large language models are generating a lot of hype for artificial intelligence, but can they assist patients and practitioners in ophthalmology? Introduction Deep learning (DL) has emerged in ophthalmology as an exciting form of artificial intelligence (AI) most commonly applied...

A novel integrated practice unit (IPU) approach to periocular skin cancer management

The COVID-19 pandemic was one of the biggest challenges to face NHS workers. However, history has repeatedly shown that times of difficulty can result in the development of significant social and technological advances. We describe our own experience of this...

Ophthalmic mentors: In conversation with Professor Harminder Dua

In the first of a series of interviews with key figures in the world of ophthalmology, Eye News speaks to Professor Harminder Dua about the future of clinical academia, his recent College presidency and Dua’s Layer. Professor Harminder Dua is...

Immunotherapy for orbital SCC

In the UK, cemiplimab is recommended for treating metastatic or locally advanced cutaneous squamous cell carcinoma (SCC) in adults when curative surgery or curative radiotherapy is not suitable. Pembrolizumab is recommended as an option for untreated metastatic or unresectable recurrent...

Therapy for limbal stem cell deficiency: cell fate after limbal stem cell transplants

“The beauty of scientific research lies in that the search for answers often yields yet more questions.” A large body of evidence points to the corneoscleral limbal location as the repository of putative epithelial stem cells [1]. Thoft proposed the...

Neovascular AMD: fresh recommendations underline standards of best practice

The management of neovascular age-related macular degeneration (nAMD) has advanced dramatically over the past seven years, with the introduction of targeted new therapies that successfully maintain or improve vision in a majority of affected individuals. It’s a fast moving field,...