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Limbal melanocytes and the stem cell niche

The cornea is continually regenerated to maintain clear vision, due to a population of stem cells located in the limbal region between the cornea and the conjunctiva. These limbal stem cells (LESC) reside in crypts in structures called the Pallisades...

Descemetorhexis without endothelial keratoplasty

This retrospective study examined outcomes of the largest reported series of eyes, which underwent Descemetorhexis without endothelial keratoplasty (DWEK) for Fuch’s endothelial dystrophy with mean 10 months of follow-up. Seventeen eyes were included in analysis; with 82.4% achieving corneal clearance...

A novel presentation of optic disc oedema with syphilis

Optic disc oedema (ODE) due to syphilis without visual compromise has been primarily attributed to papilloedema from raised intracranial pressure or optic perineuritis from optic nerve sheath inflammation. These terms were proposed before magnetic resonance imaging (MRI) was largely available....

How common are carotid-cavernous fistulas and what are the neuro-ophthalmic manifestations?

The authors present a retrospective study using the Rochester Epidemiology Project database. The aim was to establish the incidence of carotid-cavernous fistulas (CCF) and outline the associated neuro-ophthalmic patterns. Cases were identified from the database using the following criteria: a...

Capacity-building through the COECSA-RCOphth LINK – linking journals in a training and mentorship programme

The College of Ophthalmology of Central, Eastern and Southern Africa (COECSA) [1] and the Royal College of Ophthalmologists (RCOphth) [2] have a long-standing health partnership through the VISION 2020 LINKS Programme [3,4]. The LINK started a new project in 2019...

Handbook of Retinal OCT (Second Edition)

Duker et al. present the second edition of their Handbook of Retinal OCT. It’s an upgrade from their last edition in many respects – there’s an enhanced digital version, the pages have a nice glossy sheen which makes it feel...

Oculoplastics: an evolving specialty

Consultant Ophthalmic and Oculoplastic Surgeon Raman Malhotra provides an insight into this increasingly popular subspecialty of ophthalmology. Oculoplastic surgery refers to plastic, reconstructive and aesthetic surgery of the eyelids, the surrounding facial areas, orbits and lacrimal system. Its scope has...

How I overcame the hurdle that is the FRCOphth Part 1

The FRCOphth Part 1 is one of the most difficult exams in ophthalmology training, with an exam pass rate of 39.6% over the last 12 months (compared to 60.8% for FRCOphth Part 2 oral [60.8%] and written [68.7%]). Stack the...

OCT Angiography in Retinal and Macular Diseases

OCT angiography (OCT-A) is based on the concept that in a static eye, the only moving structure in the fundus of the eye is blood flowing through the vessels. This book explains how the technique allows a depth-resolved analysis and...

Practical Handbook of OCT (Retina, Choroid, Glaucoma)

With the rapid development and expansion in the usage of optical coherence tomography (OCT) technology there is always demand for a new OCT publication on the bookshelves. The operation and acquisition skills required are more easily acquired than for the...

Retinal morphology after PASCAL PRP treatment

The authors of this prospective cohort study set out to report the changes on Spectral Domain-OCT of PASCAL panretinal laser photocoagulation (PRP) treatment for proliferative diabetic retinopathy (PDR) or severe nonproliferative DR (NPDR) and the retinal morphology, from one hour...

Aflibercept treatment in polypoidal choroidal vasculopathy

The authors present a study to evaluate the anatomical and functional efficacy of aflibercept intravitreal (IVT) as a monotherapy in polypoidal choroidal vasculopathy (PCV) in a Caucasian population treated with initial three-monthly aflibercept IVT, followed by a bimonthly regimen for...