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Exploring the potential of neurodegenerative disease screening within age-related eye disease research

The authors recruited healthy controls aged between 60 and 75-years-old, previously enrolled into a registry as patients following cataract surgery without age-related macular degeneration (AMD). Exclusion criteria included dense cataract, retinal disease, ocular inflammatory disease, moderate glaucoma, optic neuropathy, cancer,...

Use of international interocular difference thresholds for optic neuritis diagnosis in clinical practice

Multiple sclerosis (MS) is the most common non-traumatic cause of disability in young people, and visual symptoms can be the initial manifestation in up to 20% of cases. Retinal examination can be helpful in making the correct diagnosis. The latest...

Rare presentation of giant cell arteritis in Chinese subjects

Only a few case reports of biopsy-proven GCA (BpGCA)-associated vision loss in Chinese subjects have been published. This paper presents three elderly Chinese subjects with BpGCA who presented with vision loss. A search of the literature was also conducted to...

Current concepts of the uveitis-glaucoma-hyphaema (UGH) syndrome

The authors discuss pathophysiology, aetiology and current management strategies of UGH syndrome. The clinical features of UGH are different than initial descriptions. UGH today is most often associated with posterior chamber IOLs that are not placed within the capsular bag...

Update: Non-infectious retinal vasculitis

This review article summarises the update on non-infectious retinal vasculitis (RV). It is primarily classified based on the type of retinal vessels involved and further sub-classified as occlusive or nonocclusive. Clinically it can occur as an isolated ocular entity or...

Oral Ibuprofen reduces early bleb failure in high risk trabeculectomy

In this retrospective cohort study, 288 eyes of 273 patients (mean ±SD age: 68.56 ±10.47 y; 32.60% females) with primary glaucoma who underwent trabeculectomy / phacotrabeculectomy at the Singapore National Eye Centre between April 2020 and April 2021 with a...

Transcriptomic and regulatory gene associations in open angle glaucoma

The authors report a study utilising a publicly available whole exome sequencing dataset of 28 patients with primary open angle glaucoma (POAG) and seven healthy control patients, and a transcriptomic dataset from the trabecular meshwork of four POAG patients and...

Risks to visual function from blepharokeratoconjunctivitis

This study evaluated the prevalence of blepharokeratoconjunctivitis (BKC) and prevalence of amblyopic risk factors with comparison of these rates to rates in the general US paediatric population. The authors evaluated the rate of patient reported symptoms in patients with and...

Medical Ophthalmological Society (MOSUK) Meeting 2024

by Nima Ghadiri, Medical Ophthalmology Consultant and Honorary Senior Clinical Lecturer, Liverpool. Diseases at the interface between ophthalmology and systemic medicine are like chameleons, masterful in their ability to adapt and often challenging to diagnose. These conditions don't always present...

The New Zealand National Eye Centre and the land of the long white cloud

Located southeast of Australia in the South Pacific Ocean, New Zealand (Aotearoa) is home to five million culturally diverse people. Renowned for its lush nature spanning from unexplored forests to active volcanos and snow-capped mountains, New Zealand has become both...

Orthoptic slit-lamp

Adaptations are described that allow the slit-lamp to be used to document squint disorders. Changes are made in the observation system, illumination system, for recording clinical findings and visualisation of clinical findings. The author includes the use of minus lens...

Developments in oculoplastic surgery

A study of NHS practice demonstrated significant patient-reported quality-of-life improvements from commonly performed oculoplastic operations: entropion repair, ectropion repair, ptosis repair and dacrocystorhinostomy (DCR) [1]. In recent years, surgical and non-surgical approaches to functional and aesthetic oculoplastic surgery have advanced...