You searched for "regenerative"

1513 results found

Limbal melanocytes and the stem cell niche

The cornea is continually regenerated to maintain clear vision, due to a population of stem cells located in the limbal region between the cornea and the conjunctiva. These limbal stem cells (LESC) reside in crypts in structures called the Pallisades...

Review of bupivacaine use in treatment of strabismus

This review aimed to assess the applications of bupivacaine (B) in the non-surgical treatment of strabismus in human and animal studies. Animal studies show that singly-innervated fibres with low concentrations of mitochondria and developed sarcoplasmic reticulum are more affected by...

Surgical management of 2 cases of synergistic adduction during elevation; aberrant regeneration

The authors present 2 cases with unusual findings of aberrant regeneration of the third cranial nerve palsy with coexisting sixth cranial nerve palsy. The first case was a 44-year-old male with head trauma from a road traffic accident. The second...

Insights on medical AI for ophthalmology: an update on current perspectives

Artificial intelligence (AI) has immense promise for revolutionising medical practice. Generative AI is a form of AI in which algorithms are trained on datasets that can be used to generate new content, such as text, images or video based on...

Bionic eyes: deciphering the neural circuitry of vision restoration

As the boundaries between technology and biology blur, retinal prosthetics, often dubbed ‘bionic eyes’, present a ground-breaking paradigm shift in addressing blindness. This article delves into the captivating scientific intricacies of these neural interfaces, exploring their mechanisms of action, current...

Myopic choroidal neovascularisation

This is a review article summarising the latest myopic CNV (choroidal neovascularisation) literature in the clinical experience and management outcomes for recommendation algorithm. The aetiology of the myopic CNV was discussed by the authors under the heading of the heredo-degenerative...

Imaging and histological relationship of orbital Schwannomas

This is a retrospective review of 15 patients with orbital Schwannomas comparing the radiological characteristics, in particular the signal intensity on MRI, with the histological sub-types of the tumours. Five patients had MRI imaging alone, three had CT alone and...

London-based My i-Clinic offers cutting-edge CAIRS treatment for keratoconus

Revolutionary treatment paves the way for reducing cases of degenerative eye condition My i-Clinic is spearheading the treatment of keratoconus after adopting the innovative ‘CAIRS’ procedure to treat patients. Hailed as a game-changer by experts, the minimally invasive procedure is...

Feb/Mar 2015 Quiz 1

A 79-year-old male presented to the ophthalmic emergency department with a three week history of left eye pain. He also reported visual deterioration in the left eye over the same period. He suffered from degenerative myopia, with his spectacle prescription...

Landmark review of glaucoma treatment and research published by Moorfields-led team

Four world-leading experts, including Hari Jayaram and Gus Gazzard from Moorfields, have combined their knowledge with the findings from over 150 peer-reviewed study publications to produce a landmark paper published in the Lancet.

Dramatic myopic shift due to epithelial basement membrane dystrophy

Epithelial basement membrane dystrophy (EBMD), also known as map-dot-fingerprint dystrophy, is a common anterior corneal disorder affecting approximately 2% of the population [1]. It is characterised by the abnormal maintenance of the basement membrane, resulting in protrusions into the epithelium....

Stromal cell alignment in damaged cornea

Stromal keratocytes are responsible for wound healing in the cornea following damage. Keratocytes at the site of injury become activated and differentiate to myofibroblasts which secrete extracellular matrix (ECM) to close the wound, a response mediated by transforming growth factor...