You searched for "neurological"
Things I’d tell my medical school self, had I known my first year on the job would be during a global pandemic
5 June 2020
| Nikolaos Tzoumas
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EYE - General
In a conversation with his younger self, a foundation doctor reflects on the contrast between his expectations of medicine at university and the reality of working during the coronavirus pandemic. Every doctor arrives at medical school with nervous anticipation, yet...
Photophobia: an unusual symptom of a pituitary macroadenoma
2 February 2024
| Kathryn O’Brien, Henry Z Lin, Anthony Vivian
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EYE - General
Introduction Photophobia, defined as ‘an abnormal intolerance to light’, is commonly associated with a range of both ocular and neurological pathologies such as dry eye, blepharospasm, corneal pathologies, cataracts, uveitis, retinal dystrophies, optic neuritis, migraine, meningitis, and traumatic brain injury...
New study uncovers key mechanism behind a common genetic cause of age-related visual loss
19 September 2024
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endothelial cells, age, vision loss, research, academic, new, genetics, genome, Fuchs Endothelial Corneal Dystrophy, FECD
A groundbreaking study has revealed important insights into the mechanisms behind Fuchs Endothelial Corneal Dystrophy (FECD), a common cause of age-related visual loss, providing hope for future therapeutic developments, and finding implications for other neurological diseases. FECD is a common,...
Acetylcholine receptor antibodies in the diagnosis of ocular myasthenia gravis at the Manchester Royal Eye Hospital
3 August 2023
| Nouf Alnafisee, Joanna M Jefferis
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EYE - Neuro-ophthalmology
Myasthenia gravis (MG) is the commonest autoimmune condition to affect the neuromuscular junction. In the UK, its prevalence is 15 per 10,000 [1,2] and recent studies have shown that rates are steadily increasing [3,4]. Aims of this audit The aim...
Bosch-Boonstro-Schaaff optic atrophy syndrome (BBSOAS) NR2F1 mutation
4 December 2023
| Soman Raman, Neda Qurashi, Qasim Mansoor
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EYE - Neuro-ophthalmology
An experienced ophthalmologist can make an anatomical diagnosis of childhood visual impairment based upon the surgical sieve, i.e., congenital and acquired. But an ophthalmologist cannot work in isolation to make an aetiological diagnosis – one would require the help of...
Strabismus in high myopia
The authors report the occurrence of exotropia-hypotropia complex in 15 cases of high myopia. The mean age at presentation was 23.5 years (10-35 years). Only two patients had high bilateral myopia. The mean axial length of the deviating eye was...
Excessive blinking
A case review is presented to understand the clinical implications for children presenting to ophthalmology with episodes of excessive blinking in the absence of any obvious ocular abnormalities. This retrospective review was conducted from 2011-2014. The authors contacted parents and...
Visual consequences of congenital hypothyroidism
This study evaluated the frequencies of ophthalmic abnormalities in Turkish children with a history of congenital hypothyroidism in a retrospective study of 121 children. Median age was nine months (one to 216) at initial ophthalmic examination. Forty children were ex-premature...
Characteristics and incidence of sixth nerve palsy in children with intracranial hypertension
1 August 2016
| Claire Howard
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EYE - Neuro-ophthalmology
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Paediatric intracranial hypertension, paediatric pseudotumor cerebri, sixth nerve palsy
The authors report the incidence and characteristics of sixth cranial nerve palsy in paediatric patients with intracranial hypertension. A retrospective review of records was performed in central Ohio over a three year period and nine children were found to have...
An unusual case of partial oculomotor nerve palsy
1 August 2016
| Claire Howard
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EYE - Neuro-ophthalmology
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Midbrain infarction, oculomotor nerve palsy, ptosis, upgaze palsy
The authors present an unusual case of intra-axial oculomotor nerve involvement due to midbrain infarction. The 65-year-old male patient presented with unilateral complete blepharoptosis and slight limitation of upgaze. Neurological examination revealed a complete ptosis of the left eyelid, slight...
MR- vs. LR+ for divergence insufficiency
A retrospective study was conducted to compare the efficacy of medial rectus recession and lateral rectus resection as surgical interventions for divergence insufficiency in 18 patients. These were cases of non-neurological cause. Two patients in each group required postoperative adjustment....
A case of progressive supranuclear palsy-like syndrome following aortic aneurysm repair
1 August 2015
| Claire Howard
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EYE - Neuro-ophthalmology
This original article illustrates the case of an 18-year-old woman who developed progressive supranuclear palsy-like syndrome following an uneventful aortic aneurysm repair. The patient was unaffected for the first 48 hours after surgery and then developed dysarthria, dysphagia (requiring a...
