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RTP801 as a neuroprotective and axon regenerative treatment
This paper describes the neuroprotective and axon regenerative effects of siRTP801, which is a translatable small-interfering RNA (siRNA) targeting mTOR negative regulator; RTP801, through in-vivo and in-vitro models. In-vivo studies involved an optic nerve crush rat model with intravitreal injections...Swimming in the deep end…
I’ve always been a water baby. Bathtime in our house was like a waterpark. As a child, I was often found sitting on the bottom of the pool holding my breath or trying to swim lengths when I was told...
Biomaterials and Regenerative Medicines in Ophthalmology (Second Edition)
With advancement in science and technology in the last decade, the role of biomaterials and regenerative medicines has become increasingly important in the management of various ocular disorders. This book highlights the role of biomaterials in the restoration of vision...Oertli launches the OS 4 UpTM surgical platform along with new instruments for retina and cataract surgery
Berneck, 4th September 2025 – Oertli Instrumente AG presented its surgical platform, the OS 4 UpTM, to the attendees of the Euretina and ESCRS congresses. The platform introduces forward-thinking solutions for vitreoretinal and cataract surgery and is complemented by new...
Pneumatic trabeculectomy
The authors present a novel technique which uses constant pressure air infusion via the constellation vision system (Alcon Laboratories) to prevent anterior chamber (AC) collapse and intraocular pressure fluctuations during trabeculectomy in high-risk cases. This was a prospective, interventional, non-randomised,...
Handbook of Retinal OCT (Second Edition)
Duker et al. present the second edition of their Handbook of Retinal OCT. It’s an upgrade from their last edition in many respects – there’s an enhanced digital version, the pages have a nice glossy sheen which makes it feel...How to win presentation medals
Having been to many tens of thousands of ophthalmology registrar presentation competitions and seen the types of presentations that consistently impress the judges, as well as the ones that fail to make the grade, I feel it is my humble...Internuclear ophthalmoplegia: a case study
A 44-year-old patient presents with binocular, mostly horizontal diplopia when fixating on moving objects. This has been ongoing for approximately five years. He is known to have multiple sclerosis and had an episode of optic neuritis six years prior in...
Rituximab efficacy for juvenile idiopathic arthritis
This is a retrospective study about the long-term efficacy of rituximab in patients with severe juvenile idiopathic arthritis (JIA)-associated uveitis. A total of eight patients (15 eyes) were recruited in this study in a single tertiary referral centre from Italy....We are all Hadiza
When I worked as a registrar at Newport many years ago I remember a no-nonsense corneal consultant railing about the way the tragic case of Lucie Linforth was being reported in the media. Lucie was a toddler taken into a...
Hybrid free vision screening for at-risk, low-income families
Give Kids Sight Day (GKSD) is an outreach programme at Wills Eye Hospital to provide free vision screening, ophthalmic examinations and glasses. It started in 2009 and has seen >11,000 children. Its primary aim is to reach high-risk families including...
