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My Top Five: Innovative approaches to dry AMD
Age-related macular degeneration (AMD) is one of the leading causes of irreversible blindness in the developing world with its prevalence rising alongside age. In societies characterised by ageing populations, it is imperative we explore more effective treatment to alleviate the...What's trending Oct/Nov 2025
A round-up of the eye-related hot topics that have been trending on social media over the last few weeks. #AlienEarth #TheEye One of the best shows to recently start streaming is, in my opinion, Alien: Earth. The cosmic horror of...Congenital cataract
Congenital cataract is the clouding or opacification of the lens that occurs at birth or weeks after (infantile cataract). They can be unilateral or bilateral and vary in form, size and location, and consequently the visual impact, management course and...Understanding amniotic membrane grafts
Safa Elhassan gives a brief review of amniotic membrane grafts and their application in theatre and clinic-based settings. Amniotic membrane (AM) transplant has been an established adjuvant treatment for many corneal, conjunctival and scleral disorders in ophthalmic clinical practice with...Strategies for managing neovascular AMD and DMO in routine clinical care
Treatment practice in the management of neovascular age-related macular degeneration (AMD) and diabetic macular oedema (DMO) illustrate increasing adoption of patient-tailored treatment approaches based on initial diagnosis and regular monitoring of imaging and visual outcomes in routine clinical care. The...Therapy for limbal stem cell deficiency: cell fate after limbal stem cell transplants
“The beauty of scientific research lies in that the search for answers often yields yet more questions.” A large body of evidence points to the corneoscleral limbal location as the repository of putative epithelial stem cells [1]. Thoft proposed the...Renewed momentum in ocular gene and cell therapy, broadening application to chronic disease
Gene and cell therapies offer the prospect of ground-breaking new avenues for the treatment of diseases, reflected in a renewed explosion of interest and investment in retinal gene therapy. Rod McNeil reports recent clinical trial readouts across a diverse range...
Use of YouTube videos to show surgical techniques for paediatric cataract surgery
This study aimed to assess the quality of the most highly viewed paediatric cataract surgery videos regarding surgeon proficiency and execution of key techniques. A search for congenital cataract surgery and paediatric cataract surgery was made in YouTube. The top...The last three patients: general medicine (Patient Two)
For the second reflection in this series (see Patient One here), Professor Jonathan Rees recounts his experiences of the last patient he saw as a medical registrar, telling the tragic story of a young man’s death and the risks that...
