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Fingolimod: ocular adverse effects

In this article the authors review the ocular side-effects of Fingolimod which is an oral immunomodulating drug used in the management of relapsing-remitting multiple sclerosis (RRMS). Fingolimod-associated macular oedema (FAME) is the most common ocular side-effect linked to this drug....

Long-term outcomes of intravitreal ranibizumab for neovascular AMD

This is a single centre prospective study for the long-term, whole population ‘real-world’ clinical outcomes of ranibizumab therapy in treatment-naïve patients for neovascular age-related macular degeneration (AMD). This study recorded: demographics, Early Treatment Diabetic Retinopathy Study visual acuity (ETDRS VA)...

OCT angiography and retinal vein occlusions

In this retrospective, observational case series, the authors set out to evaluate the morphology of the superficial and deep capillary plexa of eyes that suffered a retinal vein occlusion (RVO) on OCT angiography (OCTA) and compare the findings with fluorescein...

Cataract surgery in small adult eyes

This is a retrospective audit of a five year study period, between the periods of January 2006 to December 2010, where a surgical log book search was performed. The inclusion criteria of this study were intraocular lenses (IOL) power greater...

Retinal morphology after PASCAL PRP treatment

The authors of this prospective cohort study set out to report the changes on Spectral Domain-OCT of PASCAL panretinal laser photocoagulation (PRP) treatment for proliferative diabetic retinopathy (PDR) or severe nonproliferative DR (NPDR) and the retinal morphology, from one hour...

How does cataract surgery affect eyes with wet AMD?

In this retrospective cohort study the authors’ primary objective was to assess whether cataract surgery in eyes with wet age-related macular degeneration (AMD), triggered its progression. The surgical group comprised of 40 eyes versus 42 eyes in the non-surgical control...

How long to air tamponade after DMEK?

This interventional case series looked at the influence of different intraoperative air tamponade times on graft adherence after descemet membrane endothelial keratoplasty (DMEK). A total of 117 eyes with Fuchs endothelial corneal dystrophy (FECD) that underwent DMEK were included. Patients...

Adjuvant intravitreal dexamethasone implant for persistent CME

In this retrospective, cross-sectional study the authors investigate the efficiency of intravitreal dexamethasone implants (0.7mg) for cystoid macular oedema (CME) persisting, despite immunomodulatory treatment in patients with Behcets’ disease (BD). Twenty-seven eyes of 20 patients (12 males and eight females)...

Rebound phenomenon after IVT triamcinolone acetonide for macular oedema

In this retrospective study, the authors report the rebound phenomenon after intravitreal triamcinolone acetonide (IVTA) injection for macular oedema secondary to diabetic retinopathy (DR) and central (CRVO) or branch retinal vein occlusion (BRVO). The incidence of a rebound phenomenon was...

The willingness of patients to participate in an eye donation registry for research

This paper explores the willingness of ophthalmic patients to donate their eyes post-mortem for research purposes. A total of 300 German patients with a median age of 70 years (range 19-95) completed the standardised questionnaire; 45.3% were female and the...

Evaluation of Optive® in ocular discomfort after anti-VEGF intravitreal injection

In this study the authors prospectively evaluated the efficacy of Optive® eye drops after in full, then abbreviation - intravitreal injection (IVT). Patients naïve to IVT were included in the study. No artificial tear treatment was prescribed after the first...

The potential of artificial intelligence and digital health in global eye health

This article provides an overview of the current landscape of artificial intelligence (AI) and digital health in global eye health. Tan, et al. note that though significant progress has been made in global eye health over the last few decades,...