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Moorfields Eye Hospital, UCL Institute of Ophthalmology and Topcon Healthcare, Inc. launch Cascader Limited to advance AI-driven eyecare and Oculomics

Moorfields Eye Hospital NHS Foundation Trust, the UCL Institute of Ophthalmology (IoO), and Topcon Healthcare today announced the launch of Cascader Limited, a new medical technology company that aims to transform the detection and management of eye disease through artificial...

A rare case of endogenous panophthalmitis: Nidus from an E. coli urinary tract infection

Endogenous bacterial endophthalmitis (EBE) is a form of severe inflammation caused by haematogenous spread of a virulent bacterium from a nidus elsewhere in the body to intraocular tissues. It is a rare occurrence and only constitutes around 2–8% of all...

Mind the gap

As a medical student in London many moons ago, the only thing that I was mindful of was the gap between the platform and the train as I traversed the city on the underground. I first became aware of mindfulness...

My top five: Emerging alternatives to manage and treat nAMD

Wet (exudative or neovascular) age-related macular degeneration (AMD) is characterised by choroidal neovascularisation, in which new blood vessels from the choroid invade through Bruch’s membrane. These blood vessels proliferate beneath or through the retinal pigment epithelium (RPE), causing patients to...

My Top Five: Emerging alternatives to manage and treat nAMD

Wet (exudative or neovascular) age-related macular degeneration (AMD) is characterised by choroidal neovascularisation, in which new blood vessels from the choroid invade through Bruch’s membrane. These blood vessels proliferate beneath or through the retinal pigment epithelium (RPE), causing patients to...

My ophthalmic elective: focusing on myopia in Taiwan

The authors describe their elective experience and delve further into high myopia, an emerging ophthalmic disease that is increasingly recognised in and outside Asia. The medical school elective programme presents an opportunity for students to conduct learning in their chosen...

Gene therapy for inherited retinal disease: the Manchester Ocular Gene Therapy Group MDT service

The authors describe the process set up in Manchester for the optimum delivery and assessment of a new gene therapy treatment for patients with RPE65 IRD. Inherited retinal dystrophies (IRDs) are the second commonest cause of severe visual impairment in...

How common is empty sella in neuro-ophthalmology patients not suspected of raised intracranial pressure

The study aimed to assess how common the presence of empty / partially empty sella is amongst neuro-ophthalmology patients undergoing magnetic resonance imaging (MRI) excluding for papilledema and raised intracranial pressure (ICP). The study retrospectively reviewed case records of consecutive...

100 years of insulin

*Joint first authors The centenary of the discovery of insulin is a time to celebrate one of the most significant scientific discoveries of the 20th century. Background Before 1923, Type 1 diabetes mellitus [T1DM] resulted in death from severe ketoacidosis...

Seeing with fresh eyes: Snails as a system for studying sight restoration

Stowers scientists have established the apple snail as a new research organism for investigating eye regeneration, which may hold the key for restoring vision due to damage and disease. Snails are slimy, simple creatures yet one species, the apple snail,...

Clinician predictions and the perspectives of parents prior to strabismus surgery compared

The aim of this study was to assess the perspectives and concerns of parents in relation to exotropia surgery in comparison to how clinicians predicted parents would respond. Parents of children with intermittent exotropia who underwent surgery over a nine-month...

Ophthalmic learning through the lens of cognitivism and constructivism

Learning in ophthalmology is multi-faceted, from understanding the fundamentals of eye anatomy and physiology to higher order skills such as performing cataract and vitreoretinal surgery. Having a strong foundation in the basics is a necessity for higher order knowledge synthesis,...