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Gene therapy for inherited retinal disease: the Manchester Ocular Gene Therapy Group MDT service
The authors describe the process set up in Manchester for the optimum delivery and assessment of a new gene therapy treatment for patients with RPE65 IRD. Inherited retinal dystrophies (IRDs) are the second commonest cause of severe visual impairment in...
Proptosis reduction with teprotumumab versus surgical decompression
This study aims to explore whether fat-to-muscle ratio (FMR) can be used to determine the efficacy of teprotumumab when compared to surgical decompression. Simply put, a high FMR equates to more fat expansion and low FMR equates to more muscle...The paediatric cataract: an overview of the embryology and pathophysiology
In the first of the two articles (see Part 2 here) on paediatric cataracts, Samuel Aryee reviews the aetiology of this condition. Cataracts arise from opacification of the natural transparent lens, which can cause partial or total blindness. Although the...
Comparison of corneal deformation parameters in keratoconic and normal eyes
This study set out to compare biomechanical properties between normal and keratoconic eyes. It was a retrospective study evaluating 89 eyes (47 normal, 42 keratoconic) and a validation arm of 72 eyes (33 normal, 39 keratoconic) using a high speed...Ciliatech reports positive clinical results on novel glaucoma implant, CID, in 24-month post-operative follow up
Chavanod (near Annecy), France, March 29, 2023 - Ciliatech, an ophthalmology medtech company developing a new class of implant to treat glaucoma durably, announced the positive results of a 24-month post-operative follow-up on a clinical trial of CID, its first generation Cilio-scleral Inter-positioning Device.My ophthalmic elective: focusing on myopia in Taiwan
The authors describe their elective experience and delve further into high myopia, an emerging ophthalmic disease that is increasingly recognised in and outside Asia. The medical school elective programme presents an opportunity for students to conduct learning in their chosen...Code-Free Deep Learning: a step into the future of ophthalmology
A new focus has arisen within the research domain of artificial intelligence (AI) in healthcare called code-free deep learning (CFDL), and recent research demonstrates that ophthalmology is becoming one of the leading specialties in this field. Artificial intelligence (AI) is...Mind the gap
As a medical student in London many moons ago, the only thing that I was mindful of was the gap between the platform and the train as I traversed the city on the underground. I first became aware of mindfulness...
