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Neurofibromatosis type 2 – diagnosis, features and MDT approach

1 December 2021 | | EYE - Orbit, EYE - Vitreo-Retinal, EYE - Cataract, EYE - Refractive, EYE - General
NF2 is a genetic condition caused by mutation in a single gene (NF2 gene) on chromosome 22. The NF2 gene provides instructions to produce a protein called merlin, also known as schwannomin. This protein functions as a tumour suppressor, preventing...

High-stakes scenarios in retinal vein occlusion: A survey of medico-legal implications

2 October 2025 | | EYE - Vitreo-Retinal, EYE - Glaucoma
Central retinal vein occlusion (CRVO) is the second most common retinal vascular disease after diabetic retinopathy, and its clinical complexity often intersects with medico-legal scrutiny [1]. Missteps in timely diagnosis, inadequate follow-up or poor documentation can lead to patient harm...

Patient changes eye colour permanently and has brighter and whiter looking eyes

1 December 2017 | EYE - Cornea, EYE - General
In this new series, Simerdip Kaur takes a look at the latest ophthalmology-related news stories and asks which are scientific reality and which are ‘fake news’. Headline: Patient changes eye colour permanently and has brighter and whiter looking eyes If...

Does a gut-eye axis exist?

1 October 2019 | | EYE - General
Simerdip Kaur takes a look at the latest ophthalmology-related news stories and asks which are based on facts and which are ‘fake news’. Headline: Does a gut-eye axis exist? Over a decade ago, the Human Microbiome Project was launched by...

Can OCT predict Alzheimer’s disease?

5 February 2020 | | EYE - Imaging, EYE - General
Simerdip Kaur takes a look at the latest ophthalmology-related news stories and asks which are based on facts and which are ‘fake news’. Headline: Can OCT predict Alzheimer’s disease? In 1986 Hinton et al. demonstrated evidence of optic nerve degeneration...

Dramatic myopic shift due to epithelial basement membrane dystrophy

3 October 2024 | | EYE - Cornea
Epithelial basement membrane dystrophy (EBMD), also known as map-dot-fingerprint dystrophy, is a common anterior corneal disorder affecting approximately 2% of the population [1]. It is characterised by the abnormal maintenance of the basement membrane, resulting in protrusions into the epithelium....

Making the most of your foundation year rotation in ophthalmology

18 June 2025 | | EYE - General
Ophthalmology continues to be a highly desirable speciality in the UK; however, medical students usually encounter only minimal exposure, generally ranging from one to two weeks, during their studies [1]. Nevertheless, eye-related conditions represent a considerable share of presentations in...

Do steroids prevent progression to proliferative diabetic retinopathy (PDR)?

1 February 2017 | | EYE - Vitreo-Retinal
There is continuing debate on the merits of pan-retinal photocoagulation (PRP) for severe pre-proliferative and proliferative DR versus the newer therapies that inhibit vascular endothelial growth factor (VEGF). This has been hotly debated [1] following the publication of findings from...

Nanosecond laser cataract surgery

2 December 2019 | | EYE - Cataract, EYE - Refractive, EYE - General
The authors review the evidence for nanosecond laser cataract surgery: is this the future? Cataract is a leading cause of visual impairment worldwide, and cataract surgery is one of the most successful and cost-effective healthcare interventions, with a great impact...

My top five: Innovative approaches to dry AMD

2 February 2024 | | EYE - Vitreo-Retinal
Age-related macular degeneration (AMD) is one of the leading causes of irreversible blindness in the developing world with its prevalence rising alongside age. In societies characterised by ageing populations, it is imperative we explore more effective treatment to alleviate the...

Four pillars: The importance of clinical research

2 October 2025 | | EYE - General
This series explores the four pillars of advanced clinical practice and here, Rebecca Turner explores the pillar of clinical research. The role of the ophthalmic advanced nurse practitioner, as with all registered practitioners allied to ophthalmology, is on an upward...

Artificial intelligence and oculomics: Improving global health

2 June 2025 | | EYE - Imaging
The application of artificial intelligence (AI), and in particular deep learning, to high-resolution ocular imaging has led to many new discoveries, enabling the prediction of multiple different systemic diseases from ocular biomarkers. This emerging field is known as ‘oculomics’ [1]....