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Exploring the potential of neurodegenerative disease screening within age-related eye disease research
The authors recruited healthy controls aged between 60 and 75-years-old, previously enrolled into a registry as patients following cataract surgery without age-related macular degeneration (AMD). Exclusion criteria included dense cataract, retinal disease, ocular inflammatory disease, moderate glaucoma, optic neuropathy, cancer,...
Risk factors identified for glaucoma progression in paediatric glaucoma suspects
A retrospective case review was conducted of children (<18 years) identified as being glaucoma suspects using common clinical criteria or the Childhood Glaucoma Research Network definition. Exclusion criteria included penetrating ocular trauma, treated ocular hypertension / glaucoma and use of...
Blood pressure association with primary open angle glaucoma severity
This prospective observational study involved 47 patients diagnosed with primary open angle glaucoma (POAG) examined to investigate their postural blood pressure response and its potential correlation with the severity of glaucomatous optic neuropathy (GON). Participants underwent intraocular pressure and systemic...
How common is empty sella in neuro-ophthalmology patients not suspected of raised intracranial pressure
The study aimed to assess how common the presence of empty / partially empty sella is amongst neuro-ophthalmology patients undergoing magnetic resonance imaging (MRI) excluding for papilledema and raised intracranial pressure (ICP). The study retrospectively reviewed case records of consecutive...
Early structural and functional retinal changes in intermittent exotropia
This study aimed to evaluate and compare spectral domain optical coherence tomography (SD OCT) and electrophysiological measures in patients with intermittent exotropia and healthy controls, to outline changes in retinal and optic nerve structure and function. This was a cross-sectional...
Normative database of OCT measurements in children
This study aimed to establish a normative database of optical coherence tomography (OCT) (Cirrus SD-OCT) parameters and to investigate if gender, ethnicity and axial length affect these measures by evaluating the effects of age and spherical equivalent refraction (SER) in...
Are the clinical characteristics of idiopathic intracranial hypertension different in older adults
The authors present a retrospective cohort study with the aim of exploring how idiopathic intracranial hypertension (IIH) can present differently in older age groups, a group that has been relatively underrepresented in previous research. Cases were identified from a single...Demodex blepharitis: A transatlantic comparison of treatments available in the UK and US
Demodex blepharitis is widely recognised among eyecare professionals as an important cause of chronic lid margin inflammation, dry eye and ocular surface diseases. The characteristic feature for diagnosis is the presence of waxy deposit at the lash bases on slit...End stage glaucoma management
A 48-year-old female has had multiple drug treatment for glaucoma and is still losing field of vision. How do you manage this over time? This patient is at high-risk for going blind and should be managed aggressively to protect remaining...Pituitary tumours: why are they so often missed?
Part 2: Clinical varieties, anatomical considerations and case report (see also Part 1 and Part 3) For ophthalmologists there are four types of pituitary tumour to be considered, three of which are named according to the hormone secreted, along with...
The Neuro-Ophthalmology Survival Guide, 3rd Edition
Neuro-ophthalmology, a challenging ophthalmic subspecialty, demands an understanding of neuro-anatomical pathways, nuanced examination and advanced imaging. For ophthalmology trainees, foundation doctors, neurologists and emergency clinicians, it can feel daunting to frequently encounter optic neuritis, visual field defects and cranial nerve...
