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Management of a giant pigment epithelium detachment with transition from half- to full-dose aflibercept

This case report describes the management of a giant pigment epithelial detachment (PED) in neovascular age-related macular degeneration (nAMD) using half-dose aflibercept. An 80-year-old woman presented with a huge PED (maximum height 1338µm) and multiple risk factors for retinal pigment...

Unexpected diagnoses – stroke in children and homonymous hemianopia

We present the case of a 12-year-old child presenting with a few days history of left-sided visual loss. Upon further investigation with magnetic resonance imaging (MRI) she was unexpectedly diagnosed with a right-sided chronic posterior cerebral arterial territory infarct, causing...

Pharmacopoeia of the Royal Infirmary of Edinburgh

The compact volume depicted in Figure 1 bears the simple title Pharmacopoeia. The book originally belonged to the author’s father, the late John King. A pharmacist by profession, John King maintained a keen interest in matters pertaining to pharmaceutical history....

30 Years of Vision: Crafting the Next Decade

Centre for Sight 30 Years of Vision: Crafting the Next Decade

How does cataract surgery affect eyes with wet AMD?

In this retrospective cohort study the authors’ primary objective was to assess whether cataract surgery in eyes with wet age-related macular degeneration (AMD), triggered its progression. The surgical group comprised of 40 eyes versus 42 eyes in the non-surgical control...

Treat and extend for PCV

This South Korean study investigated the efficacy of a treat and extend regimen (TER) using ranibizumab to treat polypoidal choroidal vasculopathy (PCV). Twenty-nine eyes were included in this retrospective case note review. Of these, five eyes had been treated with...

Botulinum toxin after orbicularis myectomy

This is a retrospective review of 27 patients with benign essential blepharospasm who had become resistant to treatment with botulinum toxin and had therefore undergone orbicularis myectomy of the upper lids. The study compares the dose and frequency of botulinum...

Switchover study from Botox to Xeomin for facial dystonia

This study carried out in the UK compared the clinical effectiveness and efficiency of switching patients from Botox® injections to Xeomin®. This was carried out in 20 essential blepharospasm, 12 hemifacial spasm and six aberrant facial nerve regeneration patients. Patients...

An uncommon late postoperative complication of combined cataract surgery and intravitreal triamcinolone injection

Case report A 64-year-old female with diabetic maculopathy (DMO) underwent phacoemulsification with intraocular lens (IOL) implantation in her right eye combined with intravitreal triamcinolone (IVTA). Diabetes control was poor with HbA1c (IFCC) of 119mmol/mol and blood sugar level of 27mmol/L....

Home Wi-Fi / range and security tips

This issue covers two topics that relate to Wi-Fi. The first is keeping your wireless network secure and the second is extending its range. Keeping home Wi-Fi secure Let’s say the recent computer attacks that resulted in disruption to NHS...

Inverted internal limiting membrane flap vs internal limiting membrane insertion technique for large macular holes

This meta-analysis aimed to compare and evaluate the morphological and functional outcomes between the inverted internal limiting membrane (ILM) flap and ILM insertion techniques in the treatment of large macular holes (MHs). The primary outcome measures were defined by the...

Treatment efficacy of stage 4 ROP

This study aimed to determine the efficacy of combined vitrectomy and anti-VEGF injection for advanced stage 4 ROP with extensive neovascular proliferation (NF). The study included nine infants; six bilateral and three unilateral. Seven were female and the mean gestational...