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HLA-B27 anterior uveitis
HLA-B27 has previously been shown to have an association with uveitis, ankylosing spondylitis, reactive arthritis, ulcerative colitis and psoriasis. The authors of this review provide an update of the epidemiology of HLA-B27 associated ocular disorders. There is great variation amongst...
Systemic screening in adnexal lymphoma
This is a retrospective review of 119 patients diagnosed with ocular adnexal lymphoma, 85 of whom had primary adnexal disease and 34 had previously been diagnosed with lymphoma outside the ocular adnexa. Sixty-eight of the primary and 24 of the...
Acute retinal necrosis: an Indian experience
The authors of this retrospective study aimed to provide clinical outcomes in 62 eyes of 53 patients presenting with acute retinal necrosis. All eyes received intravenous acyclovir (10mg/kg tds) for 7-10 days followed by oral antiviral therapy (valaciclovir 1g tds...
Lacrimal gland carcinoma outcomes
This is retrospective review of outcomes of lacrimal gland epithelial tumours treated between 1972 and 2014 at Moorfields Eye Hospital. Seventy-nine patients were reported, comprising 53 adenoid cystic carcinomas, 15 primary adenocarcinomas and 11 carcinomas ex-pleomorphic adenoma. The authors compare...
Recurrent sebaceous gland carcinoma
In this retrospective case review study, authors report their outcomes in management of recurrent sebaceous gland carcinoma (SGC) and propose a graded protocol to manage these entities. All consecutive cases of SGC from January 2004 to December 2017 at the...
Assessing failure of laser coagulation treatment for type 1 retinopathy of prematurity
The authors present the findings of a retrospective study to examine the cause of treatment failures in type 1 retinopathy of prematurity (ROP). They reviewed the medical charts of all infants with persistent disease post laser treatment at Uppsala University...
Inverted papilloma
This is a retrospective review of 22 patients with inverted papilloma, including nine cases confined to the nasolacrimal system and 13 involving into the orbit. This is a rare disease and the report is the largest published series of periocular...
Effects of ML4 on the eye
Mucolipidosis type IV (ML4) is an autosomal recessive lysosomal storage disease and is caused by variants of the MC0LN1 gene. It often presents in young individuals with eye and ocular adnexa issues. The authors present a case report and literature...
Could internuclear ophthalmoplegia aid differential diagnosis in demyelinating conditions?
The authors present a retrospective review of individuals diagnosed with either neuromyelitis optica spectrum disorder (NMOSD) or multiple sclerosis (MS). The aim of the study was to assess the prevalence of internuclear ophthalmoplegia (INO) in both groups over a 10-year...
