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722 results found

A prospective trial of adjuvant therapy for high-risk melanoma

Patients diagnosed with iris, ciliary body or choroidal melanoma of high-risk tumour cytogenetics (monosomy 3>/= 20% of cells), were treated with adjuvant low-dose dacarbacine (DTIC) and interferon –alpha-2b (IFNA-2b), following primary treatment (enucleation, brachytherapy or resection). DTIC was given intravenously...

Tetracaine to reduce OCR

This study investigates the effects of Tetracaine eye drops on oculocardiac reflex (OCR) during strabismus surgery. A randomised controlled trial of 70 strabismus surgery patients aged two to 19 years was conducted with comparison of Tetracaine versus placebo. Demographics were...

Ozurdex in epiretinal membrane surgery

This was a prospective multicentre pilot study, looking at the effect of Ozurdex on visual acuity (VA) and central retinal thickness (CRT) in patients undergoing surgery for epiretinal membrane (ERM). Twelve eyes of 12 patients were included in the study....

Topical nonsteroidal ant-inflammatory drugs (NSAIDs) in patients undergoing cataract surgery

Inflammation is a major risk factor for the development of cystoid macular oedema (CMO) after cataract surgery, leading to breakdown of the blood-retina barrier. There is a correlation between severity of CMO and level of postoperative inflammation. Laser flare meter...

Visual and refractive outcomes and complications in FLACS versus CPS cataract surgery

This is a randomised, controlled study of 110 paired eyes from 55 patients that were randomised into either femtosecond laser-assisted cataract surgery (FLACS) or conventional phacoemulsification cataract surgery (CPS) groups. Visual, refractive outcomes, intraocular pressure (IOP) and complications were compared...

Relationship between intraocular pressure and optic nerve damage in optic nerve drusen

The authors present a retrospective study exploring the relationship between intraocular pressure (IOP) and optic nerve damage in patients with optic nerve drusen. The aim was to evaluate if patients with normal ocular pressure at the time of optic nerve...

Guideline considerations for management of paediatric traumatic cataract

This study aimed to develop guidelines for preoperative decision-making and perioperative management of paediatric traumatic cataract patients. A 24-question survey was designed to assess surgeon background, preoperative planning and testing, surgical timing, intraoperative techniques and postoperative management. Anonymous responses were...

Esotropia Duane’s syndrome (DRS) surgery

The authors aimed to compare the safety and efficacy of augmented superior rectus transposition surgery with / without medial rectus (MR) recession versus MR recession along in the treatment of esotropic DRS. This was a prospective randomised trial of 20...

ROP anti-VEGF treatment review

The purpose of this review was to consider data relating to risks and benefits of the use of anti-VEGF treatment for retinopathy of prematurity (ROP) over the past five years of 2015-2020. Ocular benefits include treatment of aggressive posterior ROP,...

Cell injection therapy for endothelial failure

This is a prospective observational study involving 11 eyes of 11 patients with pseudophakic endothelial failure who underwent human corneal endothelial cell culture (hCEC) injection therapy for endothelial failure. This study aimed to evaluate the long-term five-year postoperative data for...

Subconjunctival anaesthesia in vitreoretinal surgery

The authors present a technique that combines topical and subconjunctival anaesthesia for vitreoretinal surgery. In this ‘two-step’ procedure, three drops of proparacaine were applied to the conjunctival fornix, followed by subconjunctival lidocaine injected in three quadrants. This was compared with...

Residual esotropia surgery comparisons

The aim was to compare lateral rectus resection and plication methods in patients with residual esotropia for postoperative success rate, dose response, ipsilateral medial rectus limitations and reoperation. The study included 57 patients (31 female, 26 male) with 27 plication...