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The compendium to clinical evidence in DMO treatment

This review article summarises the current evidence base in the treatment options for diabetic macular oedema (DMO). The authors have included many real-world data studies that provided valuable insights into the optimal management of DMO. The authors argue that these...

Treatment of vertical diplopia in the reading position

This paper describes the use of slab-off prisms for the treatment of vertical diplopia in the reading position. The following data were collected: main symptom complaint, visual acuity, refractive error, binocular vision including sensory fusion and stereoacuity, alternating cover test...

Reattachment rate with pneumatic retinopexy vs pars plana vitrectomy for single break rhegmatogenous retinal detachment

This is a post-hoc analysis of two clinical trials, including patients who underwent pneumatic retinopexy (PnR) vs pars plana vitrectomy (PPV) and had met the management of primary rhegmatogenous retinal detachment outcomes randomised trial (PIVOT) criteria with a single break...

RCT of surgery to correct asymmetrical DVD

This study compared the efficacy of two procedures: (1) bilateral symmetrical anteriorisation of the inferior oblique (AIO) and (2) combined resection and AIO, in cases of asymmetrical dissociated vertical deviation (DVD). This was a prospective randomised controlled trial including 54...

Evolving towards an interventional glaucoma mindset

Traditionally, a newly diagnosed glaucoma patient would be treated first with medical therapy. As the disease progressed or the initial intervention failed to adequately control intraocular pressure (IOP), clinicians would add more drops, selective laser trabeculoplasty (SLT), repeated SLT and...

Paediatric optic disc anomalies

Anomalies of the optic nerve are relatively rare, but account for a significant proportion of sight impairment in children and adults. The recognition of these anomalies by eye health professionals is important not only due to their potential impact on...

Pituitary tumours: why are they so often missed?

Part 3: Clinical features, assessment and management (see also Part 2, and Part 1) As previously mentioned in this treatise [1] pituitary tumours are common, occur in all age groups and can present with anything from minimal visual symptoms to...

Therapy for limbal stem cell deficiency: cell fate after limbal stem cell transplants

“The beauty of scientific research lies in that the search for answers often yields yet more questions.” A large body of evidence points to the corneoscleral limbal location as the repository of putative epithelial stem cells [1]. Thoft proposed the...

Typical and atypical optic neuritis – diagnosis and initial management

Optic neuritis is a relatively common presentation to ophthalmologists in the acute setting. The vast majority are cases of ‘typical’ optic neuritis (ON) but a smaller group of conditions, so-called, ‘atypical’ optic neuritides require a different work-up and management strategy....

The lived experience of benign essential blepharospasm

Benign essential blepharospasm (BEB) is a rare neurological condition which causes involuntary sustained or intermittent muscular contraction of both eyelids and upper facial muscles which cause closure of eyelids, abnormal facial expressions and distress [1]. The term dystonia is an...

Advances and developments in medical retina

The author provides an update on late breaking clinical trial results in neovascular age-related macular degeneration (nAMD) and presentations on diabetes management from the American Academy of Ophthalmology Retina Subspecialty Day, held during the Academy’s annual meeting in Chicago, October...

Management of retinal diseases: highlights from the AAO 2019 Retina Subspecialty Day Meeting

The author highlights current debate, opinion and late breaking developments in the management of retinal diseases. The American Academy of Ophthalmology’s 2019 Retina Subspecialty Day Meeting was held on 11-12 October, 2019 in San Francisco, USA. Established and emerging innovative...