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Review of extraocular muscle biopsies and utility of biopsy in extraocular muscle enlargement

This is a retrospective case series study from Melbourne, Australia, of 93 patients with extraocular muscle (EOM) enlargement who underwent an EOM biopsy between March 1992 and January 2017. Statistical analysis was performed to compare the data between patients with...

OSCAR for anterior approach ptosis surgery

The authors report an International Council of Ophthalmology (ICO) Ophthalmology Surgical Competency Assessment Rubric (OSCAR) for anterior approach ptosis surgery. An international panel of content experts, representing Australia, India, Iran, Italy, Turkey, United Kingdom and the United States of America...

Prevalence and incidence of uveitis

Uveitis encompasses a group of diseases characterised by the inflammation of fovea uvea which are potentially vision threatening. However, the frequency of this condition is unclear. This systematic review and meta-analysis aimed to provide estimates of the frequency of uveitis...

HLA-B27 anterior uveitis

HLA-B27 has previously been shown to have an association with uveitis, ankylosing spondylitis, reactive arthritis, ulcerative colitis and psoriasis. The authors of this review provide an update of the epidemiology of HLA-B27 associated ocular disorders. There is great variation amongst...

Incidence and risk factors of late in the bag intraocular lens dislocation

The aim of this study was to identify risk factors for late in the bag dislocation over a 21 year period. Worldwide the incidence varies from 0.05% to 3.0%. In this Swedish study they report an increase in incidence in...

A phase 3 randomised trial of nicotinamide for skin cancer chemoprevention

To B3, or not to B3? That was the question asked in this controlled trial in which the authors were able to show that oral nicotinamide (vitamin B3) is able to reduce further skin cancer development in high risk patients....

Outcomes of ‘treat and extend’ for neovascular AMD

The authors report on 24-month outcomes of anti-vascular endothelial growth factor (anti-VEGF) therapy using a ‘treat and extend’ regime for treatment-naïve neovascular age-related macular degeneration (nAMD). Data for this study was collected from the Fight Retinal Blindness observational registry based...

Microvascular disease in Alport syndrome

The authors present the findings of a retrospective case-control observational study on increased microvascular disease in individuals with Alport syndrome recruited over a 21-year period. They recruited 28 males and 28 females with X-linked Alport syndrome (XLAS) and eight men...

Features of bacterial orbital cellulitis on MRI imaging

This multi-centre retrospective study from Australia and the UK examined the quantitative and qualitive parameters of magnetic resonance imaging (MRI) imaging in bacterial orbital cellulitis. Twenty MRI scans from 20 patients with pre-septal and orbital fat involvement (mean age: 40.8...