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East Bound and Down: Patrick Staropoli

One of my heroes growing up in the 70s was the iconic Formula 1 racing driver, James Hunt. At the time, if you had asked me and my primary school friends what we would most like to do for a...

East Bound and Down: Patrick Staropoli

One of my heroes growing up in the 70s was the iconic Formula 1 racing driver, James Hunt. At the time, if you had asked me and my primary school friends what we would most like to do for a...

Difference in retinoblastoma phenotypes based on maternal or paternal inheritance

The aim of this study was to explore the difference in presentation of retinoblastoma between paternal and maternal inheritance. A retrospective medical records review methodology was employed. Records of individuals diagnosed with a retinoblastoma with at least one symptomatic family...

Santorini sunlight!

In the heart of London, Hollywood icon Keanu Reeves attended his inspiring book launch event held at the Royal Festival Hall, later followed by a book signing at Waterstones in Piccadilly, London. Ticket holders included ladies from the Literacy Ladies...

An eye on novel anti-cancer agents: an evidence-based approach to external eye assessment

Novel anti-cancer therapies have led to significant advancement in cancer treatment, however, they can be associated with external eye complications. It is important to be mindful of such adverse effects during assessment of patients enrolled in clinical trials. Annually, approximately...

Ophthalmology research: lessons from the Academic Foundation Programme

The author discusses practical lessons learned during eight months of ophthalmology research as a guide for candidates considering a research themed AFP post, with general tips for anyone undertaking research whilst balancing clinical duties. Ophthalmology is already one of the...

House of cards

When I was a junior doctor in the late 1990s writing my first scientific papers, once each article was finished, I had to fill out an application form, print out multiple copies and then walk to the post office at...

Large collar diameter Jones tubes

This is the first report of the success rates of frosted Jones tubes with larger diameter, 4.5 or 5mm collars. This is a retrospective review of 29 eyes of 25 patients who underwent insertion of a large diameter collar frosted...

Surgical prediction in infantile ET

The purpose was to evaluate the preoperative factors influencing the efficacy of the surgical procedure of bilateral lateral rectus recessions. Fifty cases with at least one year follow-up were included for retrospective analysis. Mean response to surgery was 2.17±0.80 PD/mm...

Macular atrophy and choriocapillaris nonperfusion

This Japanese study compared the choriocapillaris (CC) nonperfusion area as measured on OCTA with areas of macular atrophy (MA) measured by fundus autofluoresence (FAF). A total of 44 eyes were assessed (31 were treated with anti-VEGF alone and 13 had...

An update on inherited retinal disorders (part 2): Approaches to therapy for IRDs

Part 1 of this topic can be found here There are currently no proven cures for inherited retinal disease (IRD). However, multiple avenues of research are being investigated to better understand disease mechanisms and trial potential therapies that may slow...

A phase 3 randomised trial of nicotinamide for skin cancer chemoprevention

To B3, or not to B3? That was the question asked in this controlled trial in which the authors were able to show that oral nicotinamide (vitamin B3) is able to reduce further skin cancer development in high risk patients....