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803 results found

Ocular toxicity secondary to deferoxamine

Patients with myelodysplastic syndromes can develop transfusion-related iron overload as they become dependent on recurrent blood transfusions [1]. Iron chelation therapy is indicated for the treatment of iron overload and one established example of this is deferoxamine. However, deferoxamine ocular...

Immunoglobulin G4-related ophthalmic disease – what is it? (Part 2)

Part 2: Clinical presentation and treatment (see part 1 here) Introduction IgG4-related disease (IgG4-RD) is understood to have a vast clinicopathological spectrum; nearly every organ has had reported involvement. Similarly, IgG4-related ophthalmic disease (IgG4-ROD) is known to affect nearly every...

Radiologic characteristics of cavernous venous malformations

This study is a retrospective review of cases with a preoperative radiologic diagnosis of cavernous venous malformations (CVMs) over 30 years. The aim of this study was to define imaging characteristics of CVMs, which will help differentiate these lesions from...

Ozurdex wound leakage

This letter to the editor describes two cases of wound leakage after Ozurdex injection. The first case is a man who had four previous injections for an underlying diagnosis of chronic serpiginous choroiditis, who was also on a course of...

Ciliary body granuloma masquerading as a melanoma

Introduction Sarcoidosis is a multisystem granulomatous inflammatory condition which predominantly affects the pulmonary system and intrathoracic lymph nodes, followed by ocular involvement [1]. We present an interesting patient who developed acute anterior uveitis and subsequent ciliary body granuloma clinically mimicking...

The implementation of postoperative day 1 vitrectomy telephone follow-up consultations

In this pre-COVID-19 study, the authors argue that some follow-up consultations can be done by telephone without compromising patient safety. Thirty years ago, a study by Isernhagen et al. [1] found that 52% of patients required some form of unexpected...

Observership in Dar es Salaam

In this report, both authors present their personal experiences of an observership at the Comprehensive Community Based Rehabilitation in Tanzania (CCBRT) Hospital, a large regional teaching hospital located in Dar es Salaam, with a particular focus on resource management, attitudes...

Imaging and histological relationship of orbital Schwannomas

This is a retrospective review of 15 patients with orbital Schwannomas comparing the radiological characteristics, in particular the signal intensity on MRI, with the histological sub-types of the tumours. Five patients had MRI imaging alone, three had CT alone and...

Immunotherapy for orbital SCC

In the UK, cemiplimab is recommended for treating metastatic or locally advanced cutaneous squamous cell carcinoma (SCC) in adults when curative surgery or curative radiotherapy is not suitable. Pembrolizumab is recommended as an option for untreated metastatic or unresectable recurrent...

Reflections on a twelve-year partnership: The Makassar-Dundee LINK

In the first article of a two-part series (see Part 2 here), the authors provide an overview of this hugely successful partnership and how they overcame the challenges of COVID-19. What began in 2008 as a connection between equals, has...

Gene therapy for inherited retinal disease: the Manchester Ocular Gene Therapy Group MDT service

The authors describe the process set up in Manchester for the optimum delivery and assessment of a new gene therapy treatment for patients with RPE65 IRD. Inherited retinal dystrophies (IRDs) are the second commonest cause of severe visual impairment in...

Modern practice options for UK ophthalmologists

When I spoke on setting up private practice at the annual United Kingdom & Ireland Society of Cataract & Refractive Surgeons (UKISCRS) meeting in November ’23 there was a lot of interest in different types of practice models. If we...