History A 58-year-old female patient was referred with a 2-year history, gradually enlarging, painless left upper lid lump. There was no bleeding or ulceration. She had no other eye symptoms and no other skin lesions. Her past medical history included:...
Know’st thou the land where lemon-trees do bloom,And oranges like gold in leafy gloom; A gentle wind from deep blue heaven blows, The myrtle thick, and high the laurel grows? ‘Tis there! ‘tis there, O my beloved one, I with...
Professor Robert MacLaren gave the Keeler Lecture at the Royal College of Ophthalmologists Annual Meeting in May 2019 on gene therapy for retinitis pigmentosa. We caught up with him afterwards to find out more. What are the key messages of...
Nearly 16 million Americans have dry eye, which in severe cases, may cause serious vision problems. Prevent Blindness will provide information on the condition, including symptoms, risk factors, treatment option and more.
Fenofibrate is an agonist of peroxisome proliferator-activated receptor-alpha (PPARα) which is used as a lipid-lowering agent. By reducing blood lipid levels, it can decrease retinal hard exudates which is beneficial in diabetic retinopathy (DR). FIELD and ACCORD studies show that...
“Serendipity is looking in a haystack for a needle and discovering a farmer’s daughter” – Julius Comroe Jr (Surgeon, Medical Researcher and Author) One of the attractive features of ophthalmology, apart from the good quality of life and the relatively...
This study evaluates the radiological patterns of extraocular muscle enlargement and proptosis in carotid cavernous fistulas (CCF). At least one muscle was enlarged in 27.5% of cases. The inferior rectus was most commonly enlarged, followed by the medial rectus. Proptosis...
The authors present a systematic review and meta-analysis evaluating the prevalence and aetiology of strabismus in individuals with Down syndrome, with particular focus on ethnic variation in the esotropia to exotropia ratio. Data from multiple studies across diverse populations were...
My father used to say that humanity is divided into those that see the world through a moral framework and recognise their place within it, and Tories. When a concerned mother came to the paediatric clinic bearing literature from the...
The authors present eight cases of ocular neuromyotonia (ONM) with an overview of the pathophysiology, aetiology, clinical presentations and possible treatments. Diagnosis was made only after thorough and repeated orthoptic examinations and review of medication history. An overview of the...
Age-related macular degeneration (AMD) is the third leading cause of blindness (behind cataract and refractive error). The authors present the results of the Global Burden of Disease (GBD) 2015 study, which included 195 countries. The disability-adjusted life years (DALY) due...
In this study the authors used the Pediatric Quality of Life Inventory (version 4.0) to evaluate impact of strabismus on health-related quality of life in Portuguese children. This was a prospective study of children aged 5–12 years over a nine-month...