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Quiz Aug/Sep 2022

History A 58-year-old female patient was referred with a 2-year history, gradually enlarging, painless left upper lid lump. There was no bleeding or ulceration. She had no other eye symptoms and no other skin lesions. Her past medical history included:...

How a calcified Soemmerring ring was removed from the vitreous cavity when the cutter and forceps failed to do so

Know’st thou the land where lemon-trees do bloom,And oranges like gold in leafy gloom; A gentle wind from deep blue heaven blows, The myrtle thick, and high the laurel grows? ‘Tis there! ‘tis there, O my beloved one, I with...

In conversation with Robert MacLaren

Professor Robert MacLaren gave the Keeler Lecture at the Royal College of Ophthalmologists Annual Meeting in May 2019 on gene therapy for retinitis pigmentosa. We caught up with him afterwards to find out more. What are the key messages of...

Dry Eye Awareness Month 2025

Nearly 16 million Americans have dry eye, which in severe cases, may cause serious vision problems. Prevent Blindness will provide information on the condition, including symptoms, risk factors, treatment option and more.

Fenofibrate and diabetic retinopathy

Fenofibrate is an agonist of peroxisome proliferator-activated receptor-alpha (PPARα) which is used as a lipid-lowering agent. By reducing blood lipid levels, it can decrease retinal hard exudates which is beneficial in diabetic retinopathy (DR). FIELD and ACCORD studies show that...

Serendipity

“Serendipity is looking in a haystack for a needle and discovering a farmer’s daughter” – Julius Comroe Jr (Surgeon, Medical Researcher and Author) One of the attractive features of ophthalmology, apart from the good quality of life and the relatively...

EOM enlargement in carotid cavernous fistulas

This study evaluates the radiological patterns of extraocular muscle enlargement and proptosis in carotid cavernous fistulas (CCF). At least one muscle was enlarged in 27.5% of cases. The inferior rectus was most commonly enlarged, followed by the medial rectus. Proptosis...

Ethnic variation in strabismus patterns in Down syndrome

The authors present a systematic review and meta-analysis evaluating the prevalence and aetiology of strabismus in individuals with Down syndrome, with particular focus on ethnic variation in the esotropia to exotropia ratio. Data from multiple studies across diverse populations were...

The Irlen Experience

My father used to say that humanity is divided into those that see the world through a moral framework and recognise their place within it, and Tories. When a concerned mother came to the paediatric clinic bearing literature from the...

Ocular neuromyotonia features

The authors present eight cases of ocular neuromyotonia (ONM) with an overview of the pathophysiology, aetiology, clinical presentations and possible treatments. Diagnosis was made only after thorough and repeated orthoptic examinations and review of medication history. An overview of the...

The global burden of age-related macular degeneration

Age-related macular degeneration (AMD) is the third leading cause of blindness (behind cataract and refractive error). The authors present the results of the Global Burden of Disease (GBD) 2015 study, which included 195 countries. The disability-adjusted life years (DALY) due...

Quality of life scores in strabismic children

In this study the authors used the Pediatric Quality of Life Inventory (version 4.0) to evaluate impact of strabismus on health-related quality of life in Portuguese children. This was a prospective study of children aged 5–12 years over a nine-month...